MedKoo Cat#: 341316 | Name: Dixanthogen

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dixanthogen is an ectoparasiticide.

Chemical Structure

Dixanthogen
Dixanthogen
CAS#502-55-6

Theoretical Analysis

MedKoo Cat#: 341316

Name: Dixanthogen

CAS#: 502-55-6

Chemical Formula: C6H10O2S4

Exact Mass: 241.9564

Molecular Weight: 242.38

Elemental Analysis: C, 29.73; H, 4.16; O, 13.20; S, 52.91

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Synonym
Dixanthogen; BRN 1781595; BRN-1781595; BRN1781595.
IUPAC/Chemical Name
Thioperoxydicarbonic acid (((HO)C(S)S)2), diethyl ester
InChi Key
FVIGODVHAVLZOO-UHFFFAOYSA-N
InChi Code
InChI=1S/C6H10O2S4/c1-3-7-5(9)11-12-6(10)8-4-2/h3-4H2,1-2H3
SMILES Code
CCOC(SSC(OCC)=S)=S
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Dixanthogen is an ectoparasiticide.
In vitro activity:
TBD
In vivo activity:
TBD
Solvent mg/mL mM
Solubility
DMSO 149.0 614.73
Ethanol 48.0 198.03
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 242.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Yekeler M, Yekeler H. Molecular modeling study on the relative stabilities of the flotation products for arsenic-containing minerals: dixanthogens and arsenic(III) xanthates. J Colloid Interface Sci. 2005 Apr 15;284(2):694-7. PubMed PMID: 15780312. 2: Brandrup F, Weismann K. [Treatment of scabies now as the dixanthogen ointment 5 and 10 per cent is no longer available]. Ugeskr Laeger. 1990 Sep 17;152(38):2751-2. Danish. PubMed PMID: 1699338. 3: Benson AM, Hunkeler MJ, York JL. Mouse hepatic glutathione transferase isoenzymes and their differential induction by anticarcinogens. Specificities of butylated hydroxyanisole and bisethylxanthogen as inducers of glutathione transferases in male and female CD-1 mice. Biochem J. 1989 Aug 1;261(3):1023-9. PubMed PMID: 2803232; PubMed Central PMCID: PMC1138931. 4: Ford DB, Benson AM. Differential responses of mouse UDP-glucuronosyltransferases and beta-glucuronidase to disulfiram and related compounds. Biochem Biophys Res Commun. 1988 May 31;153(1):149-55. PubMed PMID: 2837196. 5: Ivaska A, Leppinen J. Determination of trace amounts of the flotation collectors ethyl xanthate and diethyl dithiophosphate in aqueous solutions by cathodic stripping voltammetry. Talanta. 1986 Oct;33(10):801-6. PubMed PMID: 18964204. 6: Benson AM, Barretto PB, Stanley JS. Induction of DT-diaphorase by anticarcinogenic sulfur compounds in mice. J Natl Cancer Inst. 1986 Mar;76(3):467-73. PubMed PMID: 2419622. 7: Benson AM, Barretto PB. Effects of disulfiram, diethyldithiocarbamate, bisethylxanthogen, and benzyl isothiocyanate on glutathione transferase activities in mouse organs. Cancer Res. 1985 Sep;45(9):4219-23. PubMed PMID: 2992773. 8: Knudsen EA, Pedersen TG. [Treatment of scabies with hexicide and dixanthogen]. Ugeskr Laeger. 1979 Oct 22;141(43):2965-6. Danish. PubMed PMID: 93335. 9: Steger HF. Determination of the elemental sulphur content of minerals and ores. Talanta. 1976 May;23(5):395-7. PubMed PMID: 18961882. 10: Prasad MS. Reduction and determination of dixanthogens. Talanta. 1971 Jun;18(6):649-52. PubMed PMID: 18960926. 11: Pohlandt C, Cook EB, Steele TW. Determination of small quantities of xanthate. Talanta. 1969 Aug;16(8):1129-35. PubMed PMID: 18960617. 12: SPRENCHER A. [A dixanthogen in the treatment of scabies (transl.)]. Arq Cir Clin Exp. 1948 Sep-Oct;32(287):109-11. Portuguese. PubMed PMID: 18102866. 13: HEILESEN B. The treatment of scabies with dixanthogen liniment. Acta Derm Venereol. 1948;28(5):515-7. PubMed PMID: 18100127. 14: DANBOLT N. The new remedy against scabies, dixanthogen ointment; Dixan Nyco. Acta Derm Venereol. 1945;26(1):103. PubMed PMID: 21005785.