CRANAD-102 | CAS#2685738-66-1 | sAβ Probe

MedKoo Cat#: 564132 | Name: CRANAD-102

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CRANAD-102 is a probe for selectively detecting sAβ species in Alzheimer's disease (AD).

Chemical Structure

CRANAD-102

CAS#2685738-66-1

Theoretical Analysis

MedKoo Cat#: 564132

Name: CRANAD-102

CAS#: 2685738-66-1

Chemical Formula: C40H53BF2N4O3

Exact Mass: 686.4179

Molecular Weight: 686.70

Elemental Analysis: C, 69.96; H, 7.78; B, 1.57; F, 5.53; N, 8.16; O, 6.99

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

CRANAD-102; CRANAD102; CRANAD 102

IUPAC/Chemical Name

5,5'-((1E,1'E)-(5-(3-(2,6-dimethylphenoxy)propyl)-2,2-difluoro-2H-1lambda3,3,2lambda4-dioxaborinine-4,6-diyl)bis(ethene-2,1-diyl))bis(N,N-dipropylpyridin-2-amine)

InChi Key

XSHWAAKMQVGZPN-NWILIBCHSA-N

InChi Code

InChI=1S/C40H53BF2N4O3/c1-7-24-46(25-8-2)38-22-18-33(29-44-38)16-20-36-35(15-12-28-48-40-31(5)13-11-14-32(40)6)37(50-41(42,43)49-36)21-17-34-19-23-39(45-30-34)47(26-9-3)27-10-4/h11,13-14,16-23,29-30H,7-10,12,15,24-28H2,1-6H3/b20-16+,21-17+

SMILES Code

FB1(F)O=C(/C=C/C2=CN=C(N(CCC)CCC)C=C2)C(CCCOC3=C(C)C=CC=C3C)=C(/C=C/C4=CN=C(N(CCC)CCC)C=C4)O1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 686.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Li Y, Yang J, Liu H, Yang J, Du L, Feng H, Tian Y, Cao J, Ran C. Tuning the stereo-hindrance of a curcumin scaffold for the selective imaging of the soluble forms of amyloid beta species. Chem Sci. 2017 Nov 1;8(11):7710-7717. doi: 10.1039/c7sc02050c. Epub 2017 Sep 15. PubMed PMID: 29568434; PubMed Central PMCID: PMC5851342. 2: Yang J, Yang J, Li Y, Xu Y, Ran C. Near-infrared Fluorescence Ocular Imaging (NIRFOI) of Alzheimer's Disease. Mol Imaging Biol. 2018 May 25. doi: 10.1007/s11307-018-1213-z. [Epub ahead of print] PubMed PMID: 29802553.