MedKoo Cat#: 561841 | Name: Borofalan non-labled
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Borofalan, also known as SPM 011 is an antineoplastic adjuvant therapy used in Boron neutron capture therapy (BNCT). Boron Neutron Capture Therapy (BNCT) is a high-capture cross-section of thermal neutrons using boron-containing ( 10 B) drugs, with 10 B(n,α) 7 Li neutron capture and nuclear splitting reactions. BNCT using C-BENS with borofalan (10B) is a promising treatment option for patients with R-SCC or R/LA-nSCC of the head and neck. Note: The product we can supply is a non-label version of Borofalan.

Chemical Structure

Borofalan non-labled
Borofalan non-labled
CAS# 76410-58-7 (non-labeled)

Theoretical Analysis

MedKoo Cat#: 561841

Name: Borofalan non-labled

CAS#: 76410-58-7 (non-labeled)

Chemical Formula: C9H12BNO4

Exact Mass: 209.0859

Molecular Weight: 209.00

Elemental Analysis: C, 51.72; H, 5.79; B, 5.17; N, 6.70; O, 30.62

Price and Availability

Size Price Availability Quantity
1g USD 350.00 2 Weeks
2g USD 550.00 2 Weeks
5g USD 950.00 2 Weeks
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Synonym
Borofalan; 4-Borono-L-phenylalanine; 4-(Dihydroxyboryl)-L-phenylalanine; 4-Dihydroxyborylphenylalanine; L-BPA L-p-Boronophenylalanine; SPM011; SPM-011; SPM 011;
IUPAC/Chemical Name
L-4-Boronophenylalanine,
InChi Key
NFIVJOSXJDORSP-QMMMGPOBSA-N
InChi Code
InChI=1S/C9H12BNO4/c11-8(9(12)13)5-6-1-3-7(4-2-6)10(14)15/h1-4,8,14-15H,5,11H2,(H,12,13)/t8-/m0/s1
SMILES Code
N[C@@H](CC1=CC=C(B(O)O)C=C1)C(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Boron neutron capture therapy (BNCT) can be performed without reactors due to development of cyclotron-based epithermal neutron source (C-BENS), which is optimized for treatment for deeper-seated tumors

Preparing Stock Solutions

The following data is based on the product molecular weight 209.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL