MedKoo Cat#: 125988 | Name: Boronophenylalanine HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Borofalan, also known as SPM 011 is an antineoplastic adjuvant therapy used in Boron neutron capture therapy (BNCT). Boron Neutron Capture Therapy (BNCT) is a high-capture cross-section of thermal neutrons using boron-containing ( 10 B) drugs, with 10 B(n,α) 7 Li neutron capture and nuclear splitting reactions. BNCT using C-BENS with borofalan (10B) is a promising treatment option for patients with R-SCC or R/LA-nSCC of the head and neck. Note: The product we can supply is a non-label version of Borofalan.

Chemical Structure

Boronophenylalanine HCl
Boronophenylalanine HCl
CAS#76410-59-8 (non labeled HCl)

Theoretical Analysis

MedKoo Cat#: 125988

Name: Boronophenylalanine HCl

CAS#: 76410-59-8 (non labeled HCl)

Chemical Formula: C9H13BClNO4

Exact Mass: 245.0626

Molecular Weight: 245.47

Elemental Analysis: C, 44.04; H, 5.34; B, 4.40; Cl, 14.44; N, 5.71; O, 26.07

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Boronophenylalanine HCl; Boronophenylalanine hydrochloride; 76410-59-8; L-Phenylalanine, 4-borono-, hydrochloride; (S)-2-Amino-3-(4-boronophenyl)propanoic acid hydrochloride
IUPAC/Chemical Name
(S)-2-amino-3-(4-boronophenyl)propanoic acid hydrochloride
InChi Key
ITAYDCRFNXQNBL-QRPNPIFTSA-N
InChi Code
InChI=1S/C9H12BNO4.ClH/c11-8(9(12)13)5-6-1-3-7(4-2-6)10(14)15;/h1-4,8,14-15H,5,11H2,(H,12,13);1H/t8-;/m0./s1
SMILES Code
N[C@H](C(O)=O)CC1=CC=C(C=C1)B(O)O.Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 245.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL