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MedKoo Cat#: 584701 | Name: ME 1220

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ME 1220 exhibits broad antibacterial activity against both Gram-positive and Gram-negative bacteria.

Chemical Structure

ME 1220
ME 1220
CAS#106061-25-0

Theoretical Analysis

MedKoo Cat#: 584701

Name: ME 1220

CAS#: 106061-25-0

Chemical Formula: C22H22N6O7S3

Exact Mass: 578.0712

Molecular Weight: 578.63

Elemental Analysis: C, 45.67; H, 3.83; N, 14.52; O, 19.35; S, 16.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ME 1220; ME-1220; ME1220
IUPAC/Chemical Name
Pyridinium, 4-(((7-(((2-amino-4-thiazolyl)(ethoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)thio)-1-(carboxymethyl)-, hydroxide, inner salt, (6R-(6alpha,7beta(Z)))-
InChi Key
KVOGDGBIJZGUHF-WHRDSVKCSA-N
InChi Code
InChI=1S/C22H22N6O7S3/c1-2-35-26-15(13-10-38-22(23)24-13)18(31)25-16-19(32)28-17(21(33)34)11(9-37-20(16)28)8-36-12-3-5-27(6-4-12)7-14(29)30/h3-6,10,16,20H,2,7-9H2,1H3,(H4-,23,24,25,29,30,31,33,34)/b26-15-/t16-,20-/m1/s1
SMILES Code
O=C(C[N+]1=CC=C(SCC(CS[C@]2([H])[C@@H]3NC(/C(C4=CSC(N)=N4)=N\OCC)=O)=C(C(O)=O)N2C3=O)C=C1)[O-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 578.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Okamoto R, Tamura A, Yoshida T, Komiya I, Ogino H, Inouye S, Kondo S, Inoue M, Mitsuhashi S. In vitro and in vivo antibacterial activities of ME1220 and ME1221, novel cephalosporins. Drugs Exp Clin Res. 1991;17(4):205-12. PubMed PMID: 1794294.

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