MedKoo Cat#: 526388 | Name: HUN85199
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

HUN85199, also known as B-Raf inhibitor 1 dihydrochloride, is a novel potent and selective B-Raf inhibitor. HUN85199 has CAS#1191385-19-9, was first reported in Journal of Medicinal Chemistry (2009), 52(20), 6189-6192. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

HUN85199
HUN85199
CAS#1191385-19-9 (HCl)

Theoretical Analysis

MedKoo Cat#: 526388

Name: HUN85199

CAS#: 1191385-19-9 (HCl)

Chemical Formula: C26H21Cl3N8

Exact Mass: 550.0955

Molecular Weight: 551.86

Elemental Analysis: C, 56.59; H, 3.84; Cl, 19.27; N, 20.31

Price and Availability

Size Price Availability Quantity
100mg USD 1,050.00 2 Weeks
200mg USD 1,650.00 2 Weeks
500mg USD 2,450.00 2 Weeks
1g USD 3,650.00 2 Weeks
2g USD 6,250.00 2 Weeks
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Related CAS #
1093100-40-3 (free base) 1191385-19-9 (HCl)
Synonym
B-Raf inhibitor 1 dihydrochloride; HUN85199; HUN-85199; HUN 85199;
IUPAC/Chemical Name
1-N-(4-Chlorophenyl)-6-methyl-5-N-[3-(7H-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine dihydrochloride
InChi Key
HRLQRNBAJCQMMG-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H19ClN8.2ClH/c1-15-4-9-19-18(10-12-29-24(19)34-17-7-5-16(27)6-8-17)21(15)35-25-20(3-2-11-28-25)22-23-26(32-13-30-22)33-14-31-23;;/h2-14H,1H3,(H,28,35)(H,29,34)(H,30,31,32,33);2*1H
SMILES Code
CC1=C(NC2=NC=CC=C2C3=C4NC=NC4=NC=N3)C5=C(C(NC6=CC=C(Cl)C=C6)=NC=C5)C=C1.[H]Cl.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM
Solubility
Soluble in DMSO 0.0 0.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 551.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL