OX02983 is a novel anthelmintic agent, immobilising whipworm and reducing the ability of embryonated T. muris eggs to establish infection in the mouse host in vivo. OX02983 is a new class of anthelmintic, active against both egg and adult stages of Trichuris parasites. OX02983 demonstrated encouraging selectivity for the parasite, and importantly show considerable scope for further optimisation to improve potency and pharmacokinetic properties with the aim of developing a clinical agent.
MedKoo Cat#: 525869
Name: OX02983
CAS#: N/A
Chemical Formula: C22H20N2O2
Exact Mass: 344.1525
Molecular Weight: 344.41
Elemental Analysis: C, 76.72; H, 5.85; N, 8.13; O, 9.29
The following data is based on the product molecular weight 344.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
