MedKoo Cat#: 555881 | Name: KRAS inhibitor-9
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

KRAS inhibitor-9, also named as DUN09716, is KRAS inhibitor with potential antitumor activity. DUN09716 was reported inn patent US 9884046. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

KRAS inhibitor-9
KRAS inhibitor-9
CAS#300809-71-6

Theoretical Analysis

MedKoo Cat#: 555881

Name: KRAS inhibitor-9

CAS#: 300809-71-6

Chemical Formula: C13H9ClN2S2

Exact Mass: 291.9896

Molecular Weight: 292.80

Elemental Analysis: C, 53.33; H, 3.10; Cl, 12.11; N, 9.57; S, 21.90

Price and Availability

Size Price Availability Quantity
100mg USD 850.00 2 Weeks
200mg USD 1,350.00 2 Weeks
500mg USD 2,150.00 2 Weeks
1g USD 3,250.00 2 Weeks
2g USD 5,450.00 2 Weeks
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Related CAS #
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Synonym
DUN09716; DUN-09716; DUN 09716; KRAS inhibitor-9; KRAS inhibitor 9; KRAS inhibitor9
IUPAC/Chemical Name
4-[(Benzo[d]thiazol-2-yl)thio]-3-chloroaniline
InChi Key
DTSNLMOLTVGCGZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H9ClN2S2/c14-9-7-8(15)5-6-11(9)17-13-16-10-3-1-2-4-12(10)18-13/h1-7H,15H2
SMILES Code
NC1=CC=C(SC2=NC3=CC=CC=C3S2)C(Cl)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM
Solubility
Soluble in DMSO 0.0 0.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 292.80 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Xie C, Li Y, Li LL, Fan XX, Wang YW, Wei CL, Liu L, Leung EL, Yao XJ. Identification of a New Potent Inhibitor Targeting KRAS in Non-small Cell Lung Cancer Cells. Front Pharmacol. 2017 Nov 14;8:823. doi: 10.3389/fphar.2017.00823. PMID: 29184501; PMCID: PMC5694459.