Olaflur HF | CAS#167887-97-0 | cariostatic

MedKoo Cat#: 584928 | Name: Olaflur HF

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Olaflur (INN, or amine fluoride 297) is a fluoride-containing substance that is an ingredient of toothpastes and solutions for the prevention of dental caries. It has been in use since 1966. Especially in combination with dectaflur, it is also used in the form of gels for the treatment of early stages of caries, sensitive teeth, and by dentists for the refluoridation of damaged tooth enamel. Olaflur is a salt consisting of an alkyl ammonium cation and fluoride as the counterion. With a long lipophilic hydrocarbon chain, the cation has surfactant properties. It forms a film layer on the surface of teeth, which facilitates incorporation of fluoride into the enamel. The top layers of the enamel's primary mineral, hydroxylapatite, are converted into the more robust fluorapatite.

Chemical Structure

Olaflur HF

CAS#6818-37-7 (HF)

Theoretical Analysis

MedKoo Cat#: 584928

Name: Olaflur HF

CAS#: 6818-37-7 (HF)

Chemical Formula: C27H60F2N2O3

Exact Mass:

Molecular Weight: 498.78

Elemental Analysis: C, 65.02; H, 12.13; F, 7.62; N, 5.62; O, 9.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

6818-37-7 (HF) 7671-49-7 (free base)

Synonym

Olaflur; AmF 297; Amine fluoride; Amine fluoride 297; GA 297; OlaFluor; Olaflur; SKF 38095J2;

IUPAC/Chemical Name

Ethanol, 2,2'-[[3-[(2-hydroxyethyl)octadecylamino]propyl]imino]bis-, dihydrofluoride

InChi Key

ZVVSSOQAYNYNPP-UHFFFAOYSA-N

InChi Code

InChI=1S/C27H58N2O3.2FH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-28(22-25-30)20-18-21-29(23-26-31)24-27-32;;/h30-32H,2-27H2,1H3;2*1H

SMILES Code

CCCCCCCCCCCCCCCCCCN(CCCN(CCO)CCO)CCO.[H]F.[H]F

Appearance

This product will be supplied as aqueous solution (concentration TBD)

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 498.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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