S 14506 HCl |CAS#286369-38-8 | 5-HT1A Receptor Agonist

MedKoo Cat#: 532609 | Name: S14506 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

S 14506 is a highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). It potentially binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity.

Chemical Structure

S14506 HCl

CAS#286369-38-8 (HCl)

Theoretical Analysis

MedKoo Cat#: 532609

Name: S14506 HCl

CAS#: 286369-38-8 (HCl)

Chemical Formula: C24H27ClFN3O2

Exact Mass: 0.0000

Molecular Weight: 443.95

Elemental Analysis: C, 64.93; H, 6.13; Cl, 7.99; F, 4.28; N, 9.47; O, 7.21

Price and Availability

Size	Price	Availability
50mg	USD 550.00	2 Weeks
100mg	USD 950.00	2 Weeks
200mg	USD 1,650.00	2 Weeks
500mg	USD 2,950.00	2 Weeks
1g	USD 4,250.00	2 Weeks
2g	USD 6,950.00	2 Weeks

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Related CAS #

135722-25-7 (free base) 286369-38-8 (HCl)

Synonym

S 14506 HCl; S14506HCl; S14506 HCl; S-14506.

IUPAC/Chemical Name

4-Fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl]ethyl]benzamide hydrochloride

InChi Key

HWLZKPKZVOLFGK-UHFFFAOYSA-N

InChi Code

InChI=1S/C24H26FN3O2.ClH/c1-30-21-10-7-18-3-2-4-23(22(18)17-21)28-15-13-27(14-16-28)12-11-26-24(29)19-5-8-20(25)9-6-19;/h2-10,17H,11-16H2,1H3,(H,26,29);1H

SMILES Code

O=C(NCCN1CCN(C2=C3C=C(OC)C=CC3=CC=C2)CC1)C4=CC=C(F)C=C4.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 443.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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