ICI 169369 | CAS#85273-95-6 | 5-HT2/5-HT1C Antagonist

MedKoo Cat#: 531965 | Name: ICI 169369

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ICI 169369 is a 5-HT2/5-HT1C antagonist, that can evoke endothelium-dependent relaxation in rabbit aorta.

Chemical Structure

ICI 169369

CAS#85273-95-6

Theoretical Analysis

MedKoo Cat#: 531965

Name: ICI 169369

CAS#: 85273-95-6

Chemical Formula: C19H20N2S

Exact Mass: 308.1347

Molecular Weight: 308.44

Elemental Analysis: C, 73.99; H, 6.54; N, 9.08; S, 10.39

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

ICI 169369; ICI169369; ICI-169369.

IUPAC/Chemical Name

N,N-dimethyl-2-(3-phenylquinolin-2-yl)sulfanylethanamine

InChi Key

HYOLQGVNMQNERE-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H20N2S/c1-21(2)12-13-22-19-17(15-8-4-3-5-9-15)14-16-10-6-7-11-18(16)20-19/h3-11,14H,12-13H2,1-2H3

SMILES Code

CN(C)CCSC1=NC2=CC=CC=C2C=C1C3=CC=CC=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 308.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Pires JG, Ramage AG, Jacobs M. ICI 169,369, A 5-HT2/5-HT1C antagonist, that can evoke endothelium-dependent relaxation in rabbit aorta. J Auton Pharmacol. 1993 Aug;13(4):249-55. PubMed PMID: 8408095. 2: Nielsen TH, Tfelt-Hansen P. No effect of the 5HT2-antagonist ICI 169,369 on systolic, ergotamine-induced blood pressure changes in man. Pharmacol Toxicol. 1993 Sep;73(3):133-6. PubMed PMID: 8265515.