Icatibant is a peptidomimetic drug consisting of ten amino acids, which is a selective and specific antagonist of bradykinin B2 receptors. It has been approved by the European Commission for the symptomatic treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency.
MedKoo Cat#: 314226
Name: Icatibant
CAS#: 130308-48-4
Chemical Formula: C59H89N19O13S
Exact Mass: 1303.6608
Molecular Weight: 1304.54
Elemental Analysis: C, 54.32; H, 6.88; N, 20.40; O, 15.94; S, 2.46
Solvent | mg/mL | mM | |
---|---|---|---|
Solubility | |||
Water | 100.0 | 76.66 |
The following data is based on the product molecular weight 1,304.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |