ZTZ240 | CAS# 325457-98-5 |KCNQ2 K+ Channel Activator

MedKoo Cat#: 533008 | Name: ZTZ240

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ZTZ240 is a KCNQ2 K+ channel activator which offers a new target to treat hyperexcitability disorders.

Chemical Structure

ZTZ240

CAS# 325457-98-5

Theoretical Analysis

MedKoo Cat#: 533008

Name: ZTZ240

CAS#: 325457-98-5

Chemical Formula: C12H8ClFN2O

Exact Mass: 250.0309

Molecular Weight: 250.66

Elemental Analysis: C, 57.50; H, 3.22; Cl, 14.14; F, 7.58; N, 11.18; O, 6.38

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

ZTZ240; ZTZ 240; ZTZ-240.

IUPAC/Chemical Name

N-(6-chloropyridin-3-yl)-4-fluorobenzamide

InChi Key

URPKVELJRWKNQS-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H8ClFN2O/c13-11-6-5-10(7-15-11)16-12(17)8-1-3-9(14)4-2-8/h1-7H,(H,16,17)

SMILES Code

O=C(NC1=CC=C(Cl)N=C1)C2=CC=C(F)C=C2

Appearance

White to off-white crystalline powder.

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 250.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kornilov P, Peretz A, Attali B. Channel gating pore: a new therapeutic target. Cell Res. 2013 Sep;23(9):1067-8. doi: 10.1038/cr.2013.89. Epub 2013 Jul 9. PubMed PMID: 23835478; PubMed Central PMCID: PMC3760620.