MedKoo Cat#: 462785 | Name: Tyrosine betaine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tyrosine betaine is a fungal secondary metabolite from Ephedra roots.

Chemical Structure

Tyrosine betaine
Tyrosine betaine
CAS#69168-08-7

Theoretical Analysis

MedKoo Cat#: 462785

Name: Tyrosine betaine

CAS#: 69168-08-7

Chemical Formula: C12H17NO3

Exact Mass: 223.1208

Molecular Weight: 223.27

Elemental Analysis: C, 64.55; H, 7.67; N, 6.27; O, 21.50

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Maokonine;
IUPAC/Chemical Name
5-hydroxy-2-(2-(trimethylammonio)ethyl)benzoate
InChi Key
HTCQNXQVACMNDD-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H17NO3/c1-13(2,3)7-6-9-4-5-10(14)8-11(9)12(15)16/h4-5,8H,6-7H2,1-3H3,(H-,14,15,16)
SMILES Code
C[N+](C)(CCc1c(C([O-])=O)cc(O)cc1)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 223.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Tamada M, Endo K, Hikino H. Maokonine, hypertensive principle of Ephedra roots. Planta Med. 1978 Nov;34(3):291-3. doi: 10.1055/s-0028-1097453. PMID: 704697. 2: Kawano DF, de Carvalho MR, Machado MFM, Carmona AK, Braga GUL, Carvalho I. Biological and In silico Studies on Synthetic Analogues of Tyrosine Betaine as Inhibitors of Neprilysin - A Drug Target for the Treatment of Heart Failure. Curr Pharm Des. 2018;24(17):1899-1904. doi: 10.2174/1381612824666180515114236. PMID: 29766796. 3: Carollo CA, Calil AL, Schiave LA, Guaratini T, Roberts DW, Lopes NP, Braga GU. Fungal tyrosine betaine, a novel secondary metabolite from conidia of entomopathogenic Metarhizium spp. fungi. Fungal Biol. 2010 May- Jun;114(5-6):473-80. doi: 10.1016/j.funbio.2010.03.009. Epub 2010 Mar 27. PMID: 20943158. 4: Eggenberger F, Rowell-Rahier M. Physiological sources of variation in chemical defense ofOreina gloriosa (Coleoptera: Chrysomelidae). J Chem Ecol. 1993 Mar;19(3):395-410. doi: 10.1007/BF00994313. PMID: 24248944.