MedKoo Cat#: 526709 | Name: BRL-15572 HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BRL-15572 HCl is a 5-HT1D receptor antagonist. BRL-15572 is a useful tool for the differentiation between human 5-HT1B and 5-HT1D receptors in functional studies.

Chemical Structure

BRL-15572 HCl
BRL-15572 HCl
CAS#193611-72-2 (HCl)

Theoretical Analysis

MedKoo Cat#: 526709

Name: BRL-15572 HCl

CAS#: 193611-72-2 (HCl)

Chemical Formula: C25H28Cl2N2O

Exact Mass: 0.0000

Molecular Weight: 443.41

Elemental Analysis: C, 67.72; H, 6.37; Cl, 15.99; N, 6.32; O, 3.61

Price and Availability

Size Price Availability Quantity
10mg USD 250.00 2 Weeks
50mg USD 650.00 2 Weeks
100mg USD 1,050.00 2 Weeks
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Synonym
BRL-15572; BRL15572; BRL 15572 HCl; BRL-15,572; BRL 15,572; BRL15,572.
IUPAC/Chemical Name
1-(Diphenylmethyl)-2-(4-(3-chlorophenyl)-1-piperazinyl)ethanol hydrochloride
InChi Key
KQGJIKWDFWLCHO-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H27ClN2O.ClH/c26-22-12-7-13-23(18-22)28-16-14-27(15-17-28)19-24(29)25(20-8-3-1-4-9-20)21-10-5-2-6-11-21;/h1-13,18,24-25,29H,14-17,19H2;1H
SMILES Code
ClC1=CC(N2CCN(CC(O)C(C3=CC=CC=C3)C4=CC=CC=C4)CC2)=CC=C1.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Related: 193611-72-2 (BRL-15572 HCl) 734517-40-9 (BRL-15572 free).

Preparing Stock Solutions

The following data is based on the product molecular weight 443.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Schlicker E, Fink K, Molderings GJ, Price GW, Duckworth M, Gaster L, Middlemiss DN, Zentner J, Likungu J, Göthert M. Effects of selective h5-HT1B (SB-216641) and h5-HT1D (BRL-15572) receptor ligands on guinea-pig and human 5-HT auto- and heteroreceptors. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356(3):321-7. PubMed PMID: 9303568. 2: Price GW, Burton MJ, Collin LJ, Duckworth M, Gaster L, Göthert M, Jones BJ, Roberts C, Watson JM, Middlemiss DN. SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356(3):312-20. PubMed PMID: 9303567.