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MedKoo Cat#: 524379 | Name: BAY-27-9955

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BAY-27-9955 is glucagon receptor antagonist. It represents an innovative class of therapeutic agents for Type II diabetes.

Chemical Structure

BAY-27-9955
BAY-27-9955
CAS#202855-56-9

Theoretical Analysis

MedKoo Cat#: 524379

Name: BAY-27-9955

CAS#: 202855-56-9

Chemical Formula: C23H31FO

Exact Mass: 342.2359

Molecular Weight: 342.49

Elemental Analysis: C, 80.66; H, 9.12; F, 5.55; O, 4.67

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
BAY-27-9955; BAY27-9955; BAY 27-9955; BAY-279955; BAY 279955; BAY279955.
IUPAC/Chemical Name
1-(4'-fluoro-3,5-diisopropyl-6-propyl-[1,1'-biphenyl]-2-yl)ethanol
InChi Key
VDTWKXAPIQBOMO-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H31FO/c1-7-8-19-20(14(2)3)13-21(15(4)5)22(16(6)25)23(19)17-9-11-18(24)12-10-17/h9-16,25H,7-8H2,1-6H3
SMILES Code
CC(O)C1=C(C(C)C)C=C(C(C)C)C(CCC)=C1C2=CC=C(F)C=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 342.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bagger JI, Knop FK, Holst JJ, Vilsbøll T. Glucagon antagonism as a potential therapeutic target in type 2 diabetes. Diabetes Obes Metab. 2011 Nov;13(11):965-71. doi: 10.1111/j.1463-1326.2011.01427.x. Review. PubMed PMID: 21615669. 2: Petersen KF, Sullivan JT. Effects of a novel glucagon receptor antagonist (Bay 27-9955) on glucagon-stimulated glucose production in humans. Diabetologia. 2001 Nov;44(11):2018-24. PubMed PMID: 11719833.