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MedKoo Cat#: 597991 | Name: Palmitoyl dipeptide-7

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Palmitoyl dipeptide-7 is a peptide.

Chemical Structure

Palmitoyl dipeptide-7
Palmitoyl dipeptide-7
CAS#911813-90-6

Theoretical Analysis

MedKoo Cat#: 597991

Name: Palmitoyl dipeptide-7

CAS#: 911813-90-6

Chemical Formula: C26H51N3O5

Exact Mass: 485.3829

Molecular Weight: 485.71

Elemental Analysis: C, 64.29; H, 10.58; N, 8.65; O, 16.47

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Palmitoyl dipeptide-7; PAL-KT; Palmitoyl-lysine-threonine;
IUPAC/Chemical Name
palmitoyl-L-lysyl-L-threonine
InChi Key
FGSPQNZCLMWQAS-GPXNEJASSA-N
InChi Code
InChI=1S/C26H51N3O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-23(31)28-22(18-16-17-20-27)25(32)29-24(21(2)30)26(33)34/h21-22,24,30H,3-20,27H2,1-2H3,(H,28,31)(H,29,32)(H,33,34)/t21-,22+,24+/m1/s1
SMILES Code
C[C@@H](O)[C@@H](C(O)=O)NC([C@H](CCCCN)NC(CCCCCCCCCCCCCCC)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 485.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PubMed PMID: 23878793; PubMed Central PMCID: PMC3713876. 5: Wlodek M, Szuwarzynski M, Kolasinska-Sojka M. Effect of Supporting Polyelectrolyte Multilayers and Deposition Conditions on the Formation of 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine/1-Palmitoyl-2-oleoyl-sn-glycero- 3-phosphoethanolamine Lipid Bilayers. Langmuir. 2015 Sep 29;31(38):10484-92. doi: 10.1021/acs.langmuir.5b02560. Epub 2015 Sep 14. PubMed PMID: 26334376. 6: Shaghaghi M, Chen MT, Hsueh YW, Zuckermann MJ, Thewalt JL. Effect of Sterol Structure on the Physical Properties of 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine Membranes Determined Using (2)H Nuclear Magnetic Resonance. Langmuir. 2016 Aug 2;32(30):7654-63. doi: 10.1021/acs.langmuir.6b01401. Epub 2016 Jul 19. PubMed PMID: 27341069. 7: Ji Y, Leymarie N, Haeussler DJ, Bachschmid MM, Costello CE, Lin C. Direct detection of S-palmitoylation by mass spectrometry. Anal Chem. 2013 Dec 17;85(24):11952-9. doi: 10.1021/ac402850s. Epub 2013 Dec 6. PubMed PMID: 24279456; PubMed Central PMCID: PMC3912867. 8: Mitchell DA, Hamel LD, Ishizuka K, Mitchell G, Schaefer LM, Deschenes RJ. The Erf4 subunit of the yeast Ras palmitoyl acyltransferase is required for stability of the Acyl-Erf2 intermediate and palmitoyl transfer to a Ras2 substrate. J Biol Chem. 2012 Oct 5;287(41):34337-48. doi: 10.1074/jbc.M112.379297. Epub 2012 Aug 16. PubMed PMID: 22904317; PubMed Central PMCID: PMC3464540. 9: Son HJ, Ha SC, Hwang EY, Kim EA, Ahn JY, Choi SY, Cho SW. Roles of cysteine residues in the inhibition of human glutamate dehydrogenase by palmitoyl-CoA. BMB Rep. 2012 Dec;45(12):707-12. PubMed PMID: 23261056; PubMed Central PMCID: PMC4133811. 10: Pelletier G, Rigden M, Poon R. Diesel and biodiesels induce hepatic palmitoyl-CoA oxidase enzymatic activity through different molecular mechanisms in rats. J Biochem Mol Toxicol. 2012 Jun;26(6):235-40. doi: 10.1002/jbt.21412. Epub 2012 May 14. PubMed PMID: 22585588. 11: Jadhav AH, Mai XT, Appiah-Ntiamoah R, Lee H, Momade FW, Seo JG, Kim H. Preparation and Characterization of Palmitoyl Grafted Cellulose Nano Absorbent for the Efficient Adsorption of Pyrene from Aqueous Solution. J Nanosci Nanotechnol. 2015 Oct;15(10):7980-7. PubMed PMID: 26726451. 12: Berge RK, Vollset SE, Farstad M. Intracellular localization of palmitoyl-CoA hydrolase and palmitoyl-CoA synthetase in human blood platelets and liver. Scand J Clin Lab Invest. 1980 May;40(3):271-8. PubMed PMID: 6108603. 13: Siliprandi D, Biban C, Testa S, Toninello A, Siliprandi N. Effects of palmitoyl CoA and palmitoyl carnitine on the membrane potential and Mg2+ content of rat heart mitochondria. Mol Cell Biochem. 1992 Oct 21;116(1-2):117-23. PubMed PMID: 1282667. 14: Yasuda T, Al Sazzad MA, Jäntti NZ, Pentikäinen OT, Slotte JP. The Influence of Hydrogen Bonding on Sphingomyelin/Colipid Interactions in Bilayer Membranes. Biophys J. 2016 Jan 19;110(2):431-440. doi: 10.1016/j.bpj.2015.11.3515. PubMed PMID: 26789766; PubMed Central PMCID: PMC4724628. 15: Farstad M, Berge R. On the capacity of the beta-oxidation of palmitate and palmitoyl-esters in rat liver mitochondria. Acta Physiol Scand. 1978 Nov;104(3):337-48. PubMed PMID: 31061. 16: Berge RK, Døssland B. Differences between microsomal and mitochondrial-matrix palmitoyl-coenzyme A hydrolase, and palmitoyl-L-carnitine hydrolase from rat liver. Biochem J. 1979 Jul 1;181(1):119-25. PubMed PMID: 39553; PubMed Central PMCID: PMC1161132. 17: Yamauchi R, Watanabe S, Martín AS, Iwamoto S. Effect of α-tocopherol on the hemin-catalyzed decomposition of 1-palmitoyl-2-linoleoyl-3-sn-phosphatidylcholine 13-hydroperoxide in micelles and liposomes. Chem Phys Lipids. 2014 Dec;184:61-8. doi: 10.1016/j.chemphyslip.2014.10.001. Epub 2014 Oct 13. PubMed PMID: 25454362. 18: Cooper AN, Brown JC, Staples JF. Are long chain acyl CoAs responsible for suppression of mitochondrial metabolism in hibernating 13-lined ground squirrels? Comp Biochem Physiol B Biochem Mol Biol. 2014 Apr;170:50-7. doi: 10.1016/j.cbpb.2014.02.002. Epub 2014 Feb 20. PubMed PMID: 24561259. 19: Funkhouser JD, Batenburg JJ, Van Golde LM. Acylation of 1-palmitoyl-lysophosphatidylglycerol in a alveolar type II cells from rat lung. Biochim Biophys Acta. 1981 Oct 23;666(1):1-6. PubMed PMID: 6895328. 20: Kalli AC, Sansom MS, Reithmeier RA. Molecular dynamics simulations of the bacterial UraA H+-uracil symporter in lipid bilayers reveal a closed state and a selective interaction with cardiolipin. PLoS Comput Biol. 2015 Mar 2;11(3):e1004123. doi: 10.1371/journal.pcbi.1004123. eCollection 2015 Mar. PubMed PMID: 25729859; PubMed Central PMCID: PMC4346270.

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