Procaine Hydrochloride is a noted sodium channel blocker with a variety of inhibitory effects. In skeletal muscle, Procaine hydrochloride has been reported to inhibit calcium-induced calcium release (CICR). Procaine is also noted to act as a DNA methylation inhibitor and to cause demethylation and reactivation of methylation-silenced genes such as RARβ and GSTP1. WIF-1 is noted to be reactivated in a cancer cell line and to downregulate the Wnt canonical pathway. In studies utilizing a neuroblastoma cell line, Procaine is reported to induce neuronal apoptosis in a manner correlated with lipid solubility of the compound.
MedKoo Cat#: 318573
Name: Procaine Hydrochloride
CAS#: 51-05-8 (HCl)
Chemical Formula: C13H21ClN2O2
Exact Mass:
Molecular Weight: 272.77
Elemental Analysis: C, 57.24; H, 7.76; Cl, 13.00; N, 10.27; O, 11.73
The following data is based on the product molecular weight 272.77 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
