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MedKoo Cat#: 414501 | Name: Procainamide Free Base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Procainamide Free Base is a class Ia antiarrhythmic drug that is structurally-related to PROCAINE.

Chemical Structure

Procainamide Free Base
Procainamide Free Base
CAS#51-06-9 (free base)

Theoretical Analysis

MedKoo Cat#: 414501

Name: Procainamide Free Base

CAS#: 51-06-9 (free base)

Chemical Formula: C13H21N3O

Exact Mass: 235.1685

Molecular Weight: 235.33

Elemental Analysis: C, 66.35; H, 8.99; N, 17.86; O, 6.80

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
51-06-9 (free base); 614-39-1 (HCl)
Synonym
Procainamide Free Base; HSDB3170; HSDB-3170; HSDB 3170
IUPAC/Chemical Name
Benzamide, 4-amino-N-(2-(diethylamino)ethyl)- (9CI)
InChi Key
REQCZEXYDRLIBE-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H21N3O/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17)
SMILES Code
O=C(NCCN(CC)CC)C1=CC=C(N)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 235.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ribeiro C, Longo A. Procainamide and disopyramide. Eur Heart J. 1987 Mar;8 Suppl A:11-9. doi: 10.1093/eurheartj/8.suppl_a.11. PMID: 3556173. 2: Ellenbogen KA, Wood MA, Stambler BS. Procainamide: a perspective on its value and danger. Heart Dis Stroke. 1993 Nov-Dec;2(6):473-6. PMID: 8137053. 3: Karlsson E. Clinical pharmacokinetics of procainamide. Clin Pharmacokinet. 1978 Mar-Apr;3(2):97-107. doi: 10.2165/00003088-197803020-00001. PMID: 346289. 4: Bizjak ED, Nolan PE Jr, Brody EA, Galloway JM. Procainamide-induced psychosis: a case report and review of the literature. Ann Pharmacother. 1999 Sep;33(9):948-51. doi: 10.1345/aph.18378. PMID: 10492498. 5: Anderson JL. Conventional and sustained-release procainamide: update on pharmacology and clinical use. Clin Ther. 1985;7(5):618-40. PMID: 3902240. 6: JONES EW. Procainamide. Practitioner. 1961 Jan;186:16-8. PMID: 13790515. 7: Giardina EG. Procainamide: clinical pharmacology and efficacy against ventricular arrhythmias. Ann N Y Acad Sci. 1984;432:177-88. doi: 10.1111/j.1749-6632.1984.tb14519.x. PMID: 6084435. 8: McCrum ID, Guidry JR. Procainamide-induced psychosis. JAMA. 1978 Sep 15;240(12):1265-6. doi: 10.1001/jama.240.12.1265. PMID: 567255. 9: Landrum EM, Siegert EA, Hanlon JT, Currie MS. Prolonged thrombocytopenia associated with procainamide in an elderly patient. Ann Pharmacother. 1994 Oct;28(10):1172-6. doi: 10.1177/106002809402801008. PMID: 7841573. 10: Flanagan AD. Pharmacokinetics of a sustained release procainamide preparation. Angiology. 1982 Feb;33(2):71-7. doi: 10.1177/000331978203300201. PMID: 7039427.