Hydroxyzine Dihydrochloride | CAS# 2192-20-3 | Histamine H1 receptor antagonist

MedKoo Cat#: 318000 | Name: Hydroxyzine Dihydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hydroxyzine dihydrochloride is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite cetirizine, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.

Chemical Structure

Hydroxyzine Dihydrochloride

CAS#2192-20-3 (2HCl)

Theoretical Analysis

MedKoo Cat#: 318000

Name: Hydroxyzine Dihydrochloride

CAS#: 2192-20-3 (2HCl)

Chemical Formula: C21H29Cl3N2O2

Exact Mass: 0.0000

Molecular Weight: 447.83

Elemental Analysis: C, 56.32; H, 6.53; Cl, 23.75; N, 6.26; O, 7.15

Price and Availability

Size	Price	Availability	Quantity
1g	USD 250.00	2 Weeks
5g	USD 550.00	2 Weeks

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Related CAS #

68-88-2 (free base) 2192-20-3 (2HCl) 1244-76-4 (HCl) 10246-75-0 (pamoate) 5978-92-7 (pamoate ester)

Synonym

Hydroxyzine dihydrochloride; Hydroxyzine hydrochloride; Arcanax; Neurolax; Orgatrax; Pamoate, Hydroxyzine; Vistaril; NSC 169188; NSC-169188; NSC169188; U.C.B 4492;

IUPAC/Chemical Name

2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol;dihydrochloride

InChi Key

ANOMHKZSQFYSBR-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H

SMILES Code

ClC1=CC=C(C(N2CCN(CCOCCO)CC2)C3=CC=CC=C3)C=C1.[H]Cl.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 447.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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