Hydroxyzine is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
MedKoo Cat#: 593005
Name: Hydroxyzine free base
CAS#: 68-88-2 (free base)
Chemical Formula: C21H27ClN2O2
Exact Mass: 374.1761
Molecular Weight: 374.91
Elemental Analysis: C, 67.28; H, 7.26; Cl, 9.46; N, 7.47; O, 8.53
The following data is based on the product molecular weight 374.91 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
