ZM241385 | CAS#139180-30-6 | adenosine A2A-receptor antagonist

MedKoo Cat#: 522367 | Name: ZM241385

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ZM241385 is a selective antagonist of the adenosine A2A receptor, with high affinity and specificity. Its mechanism of action involves competitive inhibition of A2A receptor activation, preventing adenosine-mediated signaling that modulates dopamine and glutamate neurotransmission. This makes it a valuable tool in neuroscience research, particularly in studying Parkinson’s disease and neurodegenerative disorders, where A2A receptor inhibition can enhance dopaminergic signaling.

Chemical Structure

ZM241385

CAS#139180-30-6

Theoretical Analysis

MedKoo Cat#: 522367

Name: ZM241385

CAS#: 139180-30-6

Chemical Formula: C16H15N7O2

Exact Mass: 337.1287

Molecular Weight: 337.34

Elemental Analysis: C, 56.97; H, 4.48; N, 29.07; O, 9.49

Price and Availability

Size	Price	Availability
100mg	USD 750.00	2 Weeks
200mg	USD 1,250.00	2 Weeks
500mg	USD 1,950.00	2 Weeks
1g	USD 2,950.00	2 Weeks
2g	USD 4,950.00	2 Weeks

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Related CAS #

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Synonym

ZM241385; ZM-241385; ZM 241385.

IUPAC/Chemical Name

4-(2-[7-Amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol

InChi Key

PWTBZOIUWZOPFT-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H15N7O2/c17-14-20-15(18-8-7-10-3-5-11(24)6-4-10)21-16-19-13(22-23(14)16)12-2-1-9-25-12/h1-6,9,24H,7-8H2,(H3,17,18,19,20,21,22)

SMILES Code

OC1=CC=C(CCNC2=NC3=NC(C4=CC=CO4)=NN3C(N)=N2)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 337.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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