MedKoo Cat#: 318065 | Name: Iophendylate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Iofendylate is a molecule used as a contrast medium. It is an absorbable iodized fatty acid of low viscosity used for roentgenography of the spinal cord, biliary tree, sinuses, and body cavities.

Chemical Structure

Iophendylate
Iophendylate
CAS#99-79-6

Theoretical Analysis

MedKoo Cat#: 318065

Name: Iophendylate

CAS#: 99-79-6

Chemical Formula: C19H29IO2

Exact Mass: 416.1212

Molecular Weight: 416.34

Elemental Analysis: C, 54.81; H, 7.02; I, 30.48; O, 7.69

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Iophendylate, Iodophendylate, Ethiodan, Ioglunide, Maiodil, Panthopaque
IUPAC/Chemical Name
ethyl 10-(4-iodophenyl)undecanoate
InChi Key
LAYLQVBQIBQVLL-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H29IO2/c1-3-22-19(21)11-9-7-5-4-6-8-10-16(2)17-12-14-18(20)15-13-17/h12-16H,3-11H2,1-2H3
SMILES Code
CC(C1=CC=C(I)C=C1)CCCCCCCCC(OCC)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 416.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gopalakrishnan CV, Mishra A, Thomas B. Iophendylate myelography induced thoracic arachnoiditis, arachnoid cyst and syrinx, four decades later. Br J Neurosurg. 2010 Dec;24(6):711-3. doi: 10.3109/02688697.2010.522746. Epub 2010 Oct 27. PubMed PMID: 20979434. 2: Hwang SW, Bhadelia RA, Wu J. Thoracic spinal iophendylate-induced arachnoiditis mimicking an intramedullary spinal cord neoplasm. Case report. J Neurosurg Spine. 2008 Mar;8(3):292-4. doi: 10.3171/SPI/2008/8/3/292. PubMed PMID: 18312083. 3: Widlus DM, Lammert GK, Brant A, Tsue T, Samphillipo MA Jr, Magee C, Starr FL, Anderson JH, White RI Jr. In vivo evaluation of iophendylate-cyanoacrylate mixtures. Radiology. 1992 Oct;185(1):269-73. PubMed PMID: 1523322. 4: Mehta HJ, Ramakantan R, Piparia DH, Hande AM, Goel A, Satoskar AR, Dastur FD. Clinical implications of acute cerebrospinal fluid changes following iophendylate myelography. J Postgrad Med. 1992 Jan-Mar;38(1):10-2. PubMed PMID: 1512716. 5: Gupta RK, Jena A, Kumar S. Iophendylate or spillage from epidermoid--a diagnostic dilemma on cranial MR imaging. Magn Reson Imaging. 1989 May-Jun;7(3):293-5. PubMed PMID: 2761362. 6: Wong CK, Woo E, Yu YL. Iophendylate-induced basal arachnoiditis. Clin Exp Neurol. 1989;26:199-204. PubMed PMID: 2642129. 7: Jack CR Jr, Gehring DG, Ehman RL, Felmlee JP. Cerebrospinal fluid-iophendylate contrast on gradient-echo MR images. Radiology. 1988 Nov;169(2):561-3. PubMed PMID: 3175007. 8: Pascuzzi RM, Roos KL, Scott JA. Chronic focal seizure disorder as a manifestation of intracranial iophendylate. Epilepsia. 1988 May-Jun;29(3):294-6. PubMed PMID: 3131136. 9: Anand AK, Halthore SN, Wani S. Iophendylate (pantopaque) and MR imaging of the spine. Comput Radiol. 1987 Jul-Aug;11(4):165-8. PubMed PMID: 3665458. 10: Hackney DB, Grossman RI, Zimmerman RA, Joseph PM, Goldberg HI, Bilaniuk LT. MR characteristics of iophendylate (Pantopaque). J Comput Assist Tomogr. 1986 May-Jun;10(3):401-3. PubMed PMID: 3486195. 11: Gupta SR, Naheedy MH, O'Hara RJ, Rubino FA. Hydrocephalus following iophendylate injection myelography with spontaneous resolution: case report and review. Comput Radiol. 1985 Nov-Dec;9(6):359-64. PubMed PMID: 3841504. 12: Smith SP, Wolpert SM. Metrizamide-iophendylate layering technique for thoracolumbar myelography. Radiology. 1984 Dec;153(3):821-2. PubMed PMID: 6494480. 13: Haughton VM, Ho KC. Arachnoid response to contrast media: a comparison of iophendylate and metrizamide in experimental animals. Radiology. 1982 Jun;143(3):699-702. PubMed PMID: 6805038. 14: Amosov IS, Nikitina RG, Mardynskaia VP, Sazonova NA, Morozova TG. [Experimental comparative study of the Soviet preparations iophendylate and myodil for myelo- and lymphography]. Vestn Rentgenol Radiol. 1981;(3):44-7. Russian. PubMed PMID: 7269206. 15: Rezaian SM, Mozafari TY. Paraplegia as a complication of myelography with iophendylate. Spine (Phila Pa 1976). 1980 May-Jun;5(3):294-5. PubMed PMID: 7394666. 16: Gardner G. The early diagnosis of acoustic tumors using posterior fossa cisternography with iophendylate. Laryngoscope. 1980 Feb;90(2):181-95. PubMed PMID: 6965516. 17: Lotz PR, Seeger JF, Gabrielsen TO. Prospective comparison of epidural venography and iophendylate myelography in the diagnosis of herniated lumbar disks. Radiology. 1980 Jan;134(1):127-32. PubMed PMID: 7350590. 18: Jones DF. Postoperative convulsions due to iophendylate (Myodil). Report of a case and review of the causes of postoperative convulsions. Anaesthesia. 1980 Jan;35(1):50-6. PubMed PMID: 6772050. 19: Kondo A, Yamasaki T, Koyama T, Ishikawa J. [Myelography of lumbar spinal canal stenosis: complication of methylglucamine iocarmate (Dimer-X) and iophendylate (Myodil) (author's transl)]. Nihon Geka Hokan. 1979 May 1;48(3):362-71. Japanese. PubMed PMID: 464725. 20: Rinaldi I. Contamination of iophendylate by glass. N Engl J Med. 1979 Jan 11;300(2):95-6. PubMed PMID: 310064.