MedKoo Cat#: 555633 | Name: TP748
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TP748, an isoxazole, is a key intermediate for fully synthetic tetracyclines.

Chemical Structure

TP748
TP748
CAS#951698-15-0

Theoretical Analysis

MedKoo Cat#: 555633

Name: TP748

CAS#: 951698-15-0

Chemical Formula: C8H12N2O

Exact Mass: 152.0950

Molecular Weight: 152.20

Elemental Analysis: C, 63.13; H, 7.95; N, 18.41; O, 10.51

Price and Availability

Size Price Availability Quantity
200mg USD 950.00 2 Weeks
500mg USD 1,850.00 2 Weeks
1g USD 2,850.00 2 Weeks
2g USD 4,850.00 2 Weeks
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Related CAS #
No Data
Synonym
TP748; TP-748; TP 748;
IUPAC/Chemical Name
5-Isoxazolemethanamine, .alpha.-ethenyl-N,N-dimethyl-
InChi Key
YAAHTZRNFDZTNK-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H12N2O/c1-4-7(10(2)3)8-5-6-9-11-8/h4-7H,1H2,2-3H3
SMILES Code
CN(C)C(C=C)C1=CC=NO1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 152.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Process Research and Development of TP-808: A Key Intermediate for the Manufacture of Synthetic Tetracyclines Wu-Yan Zhang, Chi-Li Chen, Minsheng He, Zhijian Zhu, Philip Hogan, Olga Gilicky, Nicholas Dunwoody, and Magnus Ronn Organic Process Research & Development 2017 21 (3), 377-386 DOI: 10.1021/acs.oprd.7b00003