CPUY201112 | CAS#1860793-58-3 | Hsp90 inhibitor

MedKoo Cat#: 527478 | Name: CPUY201112

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CPUY201112 is a novel inhibitor of heat shock protein Hsp90, inducing p53-mediated apoptosis in MCF-7 cells.

Chemical Structure

CPUY201112

CAS#1860793-58-3

Theoretical Analysis

MedKoo Cat#: 527478

Name: CPUY201112

CAS#: 1860793-58-3

Chemical Formula: C19H23N3O4

Exact Mass: 357.1689

Molecular Weight: 357.41

Elemental Analysis: C, 63.85; H, 6.49; N, 11.76; O, 17.91

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

CPUY 201112; CPUY-201112; CPUY201112

IUPAC/Chemical Name

(2,4-Dihydroxy-5-isopropyl-phenyl)-(2-ethoxy-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl)-methanone

InChi Key

BNTRGXQGSZZFCB-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H23N3O4/c1-4-26-19-20-9-12-10-22(6-5-15(12)21-19)18(25)14-7-13(11(2)3)16(23)8-17(14)24/h7-9,11,23-24H,4-6,10H2,1-3H3

SMILES Code

O=C(C1=CC(C(C)C)=C(O)C=C1O)N2CCC3=NC(OCC)=NC=C3C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 357.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Xu XL, Bao QC, Jia JM, Liu F, Guo XK, Zhang MY, Wei JL, Lu MC, Xu LL, Zhang XJ, You QD, Sun HP. CPUY201112, a novel synthetic small-molecule compound and inhibitor of heat shock protein Hsp90, induces p53-mediated apoptosis in MCF-7 cells. Sci Rep. 2016 Jan 8;6:19004. doi: 10.1038/srep19004. PubMed PMID: 26743233; PubMed Central PMCID: PMC4705544.