CAY10789 | CAS#123226-28-8 | CysLT1 receptor antagonist

MedKoo Cat#: 112005 | Name: CAY10789

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CAY10789 is an antagonist of the cysteinyl leukotriene 1 (CysLT1) receptor (IC50 = 2.1 µM).

Chemical Structure

CAY10789

CAS#123226-28-8

Theoretical Analysis

MedKoo Cat#: 112005

Name: CAY10789

CAS#: 123226-28-8

Chemical Formula: C17H15NO2

Exact Mass: 265.1103

Molecular Weight: 265.31

Elemental Analysis: C, 76.96; H, 5.70; N, 5.28; O, 12.06

Price and Availability

Size	Price	Availability
5mg	USD 450.00	2 Weeks
10mg	USD 750.00	2 Weeks
25mg	USD 1,250.00	2 Weeks

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Related CAS #

No Data

Synonym

CAY10789; CAY-10789; CAY 10789;

IUPAC/Chemical Name

(3-(quinolin-2-ylmethoxy)phenyl)methanol

InChi Key

FARMNDXIOAHJMF-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H15NO2/c19-11-13-4-3-6-16(10-13)20-12-15-9-8-14-5-1-2-7-17(14)18-15/h1-10,19H,11-12H2

SMILES Code

OCC1=CC(OCC2=NC3=C(C=CC=C3)C=C2)=CC=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	DMF	11.0	41.46
	DMSO	5.0	18.85
	Ethanol	11.0	41.46
	PBS (pH: 7.2)	0.1	0.53

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 265.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Fiorillo, B., Sepe, V., Conflitti, P., et al. Structural basis for developing multitarget compounds acting on cysteinyl leukotriene receptor 1 and G-protein-coupled bile acid receptor 1. J. Med. Chem. 64(22), 16512-16529 (2021).