MedKoo Cat#: 317371 | Name: Carbinoxamine Maleate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Carbinoxamine Maleate is a antihistamine and anticholinergic agent. It was first launched in the United States by the McNeil Corporation under the brand name Clistin. It is now available under the brand name Palgic as 4 mg tablets or 4 mg/5 mL liquid. It is approved by the U.S. Food and Drug Administration (FDA) (specifically at the 4 mg dose/strength) for hay fever (a.k.a. allergic rhinitis, SAR and PAR); vasomotor rhinitis; mild urticaria; angioedema, dermatographism and allergic conjunctivitis. Carbinoxamine is a histamine antagonist, specifically an H1-antagonist.

Chemical Structure

Carbinoxamine Maleate
Carbinoxamine Maleate
CAS#3505-38-2 (maleate)

Theoretical Analysis

MedKoo Cat#: 317371

Name: Carbinoxamine Maleate

CAS#: 3505-38-2 (maleate)

Chemical Formula: C20H23ClN2O5

Exact Mass: 0.0000

Molecular Weight: 406.86

Elemental Analysis: C, 59.04; H, 5.70; Cl, 8.71; N, 6.89; O, 19.66

Price and Availability

Size Price Availability Quantity
1g USD 250.00 2 Weeks
2g USD 350.00 2 Weeks
5g USD 550.00 2 Weeks
10g USD 850.00 2 Weeks
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Synonym
Histex CT; Clistin; Palgic; Rondec; Rhinopront; Carbinoxamine; NSC 62362; NSC62362; NSC-62362;
IUPAC/Chemical Name
2-((4-chlorophenyl)(pyridin-2-yl)methoxy)-N,N-dimethylethan-1-amine maleate
InChi Key
GVNWHCVWDRNXAZ-BTJKTKAUSA-N
InChi Code
InChI=1S/C16H19ClN2O.C4H4O4/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-10,16H,11-12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
SMILES Code
CN(C)CCOC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2.C(=C\C(=O)O)\C(=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 406.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Moustafa AA, Hegazy MA, Mohamed D, Ali O. Evaluation of multivariate calibration models with different pre-processing and processing algorithms for a novel resolution and quantitation of spectrally overlapped quaternary mixture in syrup. Spectrochim Acta A Mol Biomol Spectrosc. 2016 Feb 5;154:76-83. doi: 10.1016/j.saa.2015.10.010. Epub 2015 Oct 22. PubMed PMID: 26519913. 2: Wang X, Yang H, Zhou B, Wang X, Xie Y. Effect of oxidation on amine-based pharmaceutical degradation and N-Nitrosodimethylamine formation. Water Res. 2015 Jul 29;87:403-411. doi: 10.1016/j.watres.2015.07.045. [Epub ahead of print] PubMed PMID: 26469132.