MedKoo Cat#: 129018 | Name: IAJD97
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

IAJD97 is an ionizable amphiphilic Janus dendrimer (pKa = 6.46) that has been used in the generation of dendrosome nanoparticles (DNPs) for the delivery of mRNA in vivo.

Chemical Structure

IAJD97
IAJD97
CAS#2857089-36-0

Theoretical Analysis

MedKoo Cat#: 129018

Name: IAJD97

CAS#: 2857089-36-0

Chemical Formula: C41H74N2O6

Exact Mass: 690.5547

Molecular Weight: 691.05

Elemental Analysis: C, 71.26; H, 10.79; N, 4.05; O, 13.89

Price and Availability

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500mg USD 350.00 2 Weeks
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Related CAS #
No Data
Synonym
IAJD97; IAJD 97; IAJD-97
IUPAC/Chemical Name
3,4,5-tris((2-ethylhexyl)oxy)benzyl 4-(4-(2-hydroxyethyl)piperazin-1-yl)butanoate
InChi Key
BPXZZLSZIMGJNB-UHFFFAOYSA-N
InChi Code
InChI=1S/C41H74N2O6/c1-7-13-17-34(10-4)30-46-38-28-37(33-48-40(45)20-16-21-42-22-24-43(25-23-42)26-27-44)29-39(47-31-35(11-5)18-14-8-2)41(38)49-32-36(12-6)19-15-9-3/h28-29,34-36,44H,7-27,30-33H2,1-6H3
SMILES Code
O=C(CCCN1CCN(CC1)CCO)OCC2=CC(OCC(CC)CCCC)=C(C(OCC(CC)CCCC)=C2)OCC(CCCC)CC
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 691.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Zhang, D., Atochina-Vasserman, E.N., Maurya, D.S., et al. Targeted delivery of mRNA with one-component ionizable amphiphilic Janus dendrimers. J. Am. Chem. Soc. 143(43), 17975-17982 (2021). 2. Arshad, M., Atochina-Vasserman, E.N., Chenna, S.S., et al. Accelerated ten-gram-scale synthesis of one-component multifunctional sequence-defined ionizable amphiphilic Janus dendrimer 97. Biomacromolecules 25(10), 6871-6882 (2024).