Azafrin | CAS#507-61-9 | biochemical

MedKoo Cat#: 146127 | Name: Azafrin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Azafrin is a bioactive compound derived from various plant species, known for its antimicrobial, anti-inflammatory, and antioxidant properties. It has been studied for its potential to treat infections caused by resistant microorganisms, as well as its ability to mitigate oxidative stress and inflammation. Azafrin exerts its effects by interacting with cellular signaling pathways, reducing the production of inflammatory cytokines and scavenging free radicals.

Chemical Structure

Azafrin

CAS#507-61-9

Theoretical Analysis

MedKoo Cat#: 146127

Name: Azafrin

CAS#: 507-61-9

Chemical Formula: C27H38O4

Exact Mass: 426.2770

Molecular Weight: 426.60

Elemental Analysis: C, 76.02; H, 8.98; O, 15.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Azafrin;

IUPAC/Chemical Name

(2E,4E,6E,8E,10E,12E,14E)-15-((1R,2R)-1,2-dihydroxy-2,6,6-trimethylcyclohexyl)-4,9,13-trimethylpentadeca-2,4,6,8,10,12,14-heptaenoic acid

InChi Key

NYWCITDWPAZNBU-DYISAODMSA-N

InChi Code

1S/C27H38O4/c1-21(11-7-8-12-22(2)15-16-24(28)29)13-9-14-23(3)17-20-27(31)25(4,5)18-10-19-26(27,6)30/h7-9,11-17,20,30-31H,10,18-19H2,1-6H3,(H,28,29)/b8-7+,13-9+,16-15+,20-17+,21-11+,22-12+,23-14+/t26-,27-/m1/s1

SMILES Code

CC(\C=C\C=C(C)\C=C\[C@@]1(O)C(C)(C)CCC[C@@]1(C)O)=C/C=C/C=C(C)/C=C/C(O)=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 426.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Agrawal P, Laddha K, Tiwari A. Isolation and HPLC method development of azafrin from Alectra parasitica var. chitrakutensis. Nat Prod Res. 2014;28(13):940-4. doi: 10.1080/14786419.2014.896009. Epub 2014 Mar 17. PMID: 24627973. 2: Yang S, Chou G, Li Q. Cardioprotective role of azafrin in against myocardial injury in rats via activation of the Nrf2-ARE pathway. Phytomedicine. 2018 Aug 1;47:12-22. doi: 10.1016/j.phymed.2018.04.042. Epub 2018 Apr 18. PMID: 30166096. 3: Zhang X, Li C, Wang L, Fei Y, Qin W. Analysis of Centranthera grandiflora Benth Transcriptome Explores Genes of Catalpol, Acteoside and Azafrin Biosynthesis. Int J Mol Sci. 2019 Nov 29;20(23):6034. doi: 10.3390/ijms20236034. PMID: 31795510; PMCID: PMC6928798. 4: Yuan W, Liu X, Wang X, Nian Z, Wu X, Zi C, Xu S, Shen X, Wang X. Evaluating the Components, Nutrients, and Antioxidant and Anti-Inflammatory Properties of Centranthera grandiflora Benth Extracts. Nutrients. 2025 Mar 6;17(5):925. doi: 10.3390/nu17050925. PMID: 40077795; PMCID: PMC11901887. 5: Ranjana, Binwal M, Verma AK, Bawankule DU, Tiwari N, Shanker K. Stimulation of glucose uptake by glycosides from Alectra parasitica subsp. chitrakutensis (M.A. Rau) K.K. Khanna & An. Kumar: An in-vitro study of TNF-α induced insulin resistance in L6 myoblasts. Nat Prod Res. 2023 Jun;37(12):2024-2030. doi: 10.1080/14786419.2022.2112957. Epub 2022 Aug 19. PMID: 35983769. 6: Cao J, Ma Y, Fu J, Wang Z, Zhao Y, Zhong N, Zhao P. Bacillus atrophaeus DX-9 biocontrol against potato common scab involves significant changes in the soil microbiome and metabolome. aBIOTECH. 2025 Feb 18;6(1):33-49. doi: 10.1007/s42994-025-00199-3. PMID: 40060187; PMCID: PMC11889282. 7: Liang JZ. [Chemical constituents of Centranthera grandiflora]. Zhong Yao Tong Bao. 1985 May;10(5):35-6. Chinese. PMID: 2934159.