IUPAC/Chemical Name
3,3,5-trimethyl-3,11-dihydropyrano[3,2-a]carbazol-8-ol
InChi Key
VISKLVOLGCYFCW-UHFFFAOYSA-N
InChi Code
1S/C18H17NO2/c1-10-8-14-13-9-11(20)4-5-15(13)19-16(14)12-6-7-18(2,3)21-17(10)12/h4-9,19-20H,1-3H3
SMILES Code
CC1=C2OC(C)(C)C=CC2=C3NC4=CC=C(O)C=C4C3=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
279.34
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Wadanambi PM, Jayathilaka N, Seneviratne KN. A Computational Study of Carbazole Alkaloids from Murraya koenigii as Potential SARS-CoV-2 Main Protease Inhibitors. Appl Biochem Biotechnol. 2023 Jan;195(1):573-596. doi: 10.1007/s12010-022-04138-6. Epub 2022 Sep 15. PMID: 36107386; PMCID: PMC9474281.
2: Joshi T, Jain T, Mahar R, Singh SK, Srivastava P, Shukla SK, Mishra DK, Bhatta RS, Banerjee D, Kanojiya S. Pyranocarbazoles from Murraya koenigii (L.) Spreng. as antimicrobial agents. Nat Prod Res. 2018 Feb;32(4):430-434. doi: 10.1080/14786419.2017.1308363. Epub 2017 Apr 3. PMID: 28368664.
3: Mandal S, Nayak A, Kar M, Banerjee SK, Das A, Upadhyay SN, Singh RK, Banerji A, Banerji J. Antidiarrhoeal activity of carbazole alkaloids from Murraya koenigii Spreng (Rutaceae) seeds. Fitoterapia. 2010 Jan;81(1):72-4. doi: 10.1016/j.fitote.2009.08.016. Epub 2009 Aug 18. PMID: 19695314.
4: Nandan S, Singh SK, Singh P, Bajpai V, Mishra AK, Joshi T, Mahar R, Shukla SK, Mishra DK, Kanojiya S. Quantitative Analysis of Bioactive Carbazole Alkaloids in Murraya koenigii (L.) from Six Different Climatic Zones of India Using UPLC/MS/MS and Their Principal Component Analysis. Chem Biodivers. 2021 Dec;18(12):e2100557. doi: 10.1002/cbdv.202100557. Epub 2021 Oct 27. PMID: 34643999.
5: Chatterjee D, Narzish F, Borade P, Singh IP. Simultaneous quantitation of nine carbazole alkaloids from Murraya koenigii (L.) Spreng by 1H qNMR spectroscopy. Nat Prod Res. 2024 Sep;38(18):3173-3181. doi: 10.1080/14786419.2023.2219819. Epub 2023 Jun 16. PMID: 37322993.
6: Xie FZ, Ming DS, Chen RY, Yu DQ. [Studies on the chemical constituents of Murraya kwangsiensis]. Yao Xue Xue Bao. 2000 Nov;35(11):826-8. Chinese. PMID: 11218858.
7: Sadwal S, Bharati S, Dar ZA, Kaur S. Chemopreventive potential of hydroethanolic Murraya koenigii leaves extract against DMBA induced breast carcinogenesis: In-silico and in-vivo study. J Ethnopharmacol. 2024 Jan 30;319(Pt 1):117124. doi: 10.1016/j.jep.2023.117124. Epub 2023 Sep 8. PMID: 37678421.