Isopedopeptin B | CAS#unknown | Natural antibacterial agent

MedKoo Cat#: 463318 | Name: Isopedopeptin B

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Isopedopeptin B is a natural antibacterial agent with cytotoxicity and hemolytic properties against a larger panel of Gram-negative bacteria.

Chemical Structure

Isopedopeptin B

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 463318

Name: Isopedopeptin B

CAS#: unknown

Chemical Formula: C54H90N12O15

Exact Mass: 1146.6649

Molecular Weight: 1147.38

Elemental Analysis: C, 56.53; H, 7.91; N, 14.65; O, 20.92

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Isopedopeptin B; Isopedopeptin-B;

IUPAC/Chemical Name

(3S,6S,9R,12S,15S,21S,24S,27R,31R,E)-21-(2-aminoethyl)-12,27-bis(aminomethyl)-9-benzyl-6-(tert-butyl)-18-ethylidene-31-hydroxy-15-((R)-1-hydroxyethyl)-24-isobutyl-3-(methoxycarbonyl)-5,8,11,14,17,20,23,26,29-nonaoxo-4,7,10,13,16,19,22,25,28-nonaazaoctatriacontanoic acid

InChi Key

BLJYFTFWLVGGPO-VZMXICOISA-N

InChi Code

InChI=1S/C54H90N12O15/c1-10-12-13-14-18-21-33(68)26-41(69)58-39(28-56)49(76)61-36(24-30(3)4)47(74)60-35(22-23-55)46(73)59-34(11-2)45(72)65-43(31(5)67)51(78)64-40(29-57)50(77)62-37(25-32-19-16-15-17-20-32)48(75)66-44(54(6,7)8)52(79)63-38(27-42(70)71)53(80)81-9/h11,15-17,19-20,30-31,33,35-40,43-44,67-68H,10,12-14,18,21-29,55-57H2,1-9H3,(H,58,69)(H,59,73)(H,60,74)(H,61,76)(H,62,77)(H,63,79)(H,64,78)(H,65,72)(H,66,75)(H,70,71)/b34-11+/t31-,33-,35+,36+,37-,38+,39-,40+,43+,44-/m1/s1

SMILES Code

CCCCCCC[C@@H](O)CC(N[C@H](CN)C(N[C@@H](CC(C)C)C(N[C@@H](CCN)C(N/C(C(N[C@@H]([C@H](O)C)C(N[C@@H](CN)C(N[C@H](CC1=CC=CC=C1)C(N[C@@H](C(C)(C)C)C(N[C@H](C(OC)=O)CC(O)=O)=O)=O)=O)=O)=O)=C/C)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,147.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Nord C, Bjerketorp J, Levenfors JJ, Cao S, Strömstedt AA, Guss B, Larsson R, Hughes D, Öberg B, Broberg A. Isopedopeptins A-H: Cationic Cyclic Lipodepsipeptides from Pedobacter cryoconitis UP508 Targeting WHO Top- Priority Carbapenem-Resistant Bacteria. ACS Chem Biol. 2020 Oct 14. doi: 10.1021/acschembio.0c00568. Epub ahead of print. PMID: 33054165.