MedKoo Cat#: 145762 | Name: CC-1069

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CC-1069 is a potent and selective inhibitor of the enzyme histone deacetylase (HDAC). HDACs play a role in the regulation of gene expression by modifying histones, proteins around which DNA is wrapped. Inhibiting HDAC can influence the expression of genes involved in cancer cell growth, differentiation, and survival. CC-1069 has been studied for its potential use in treating certain types of cancer, including hematologic malignancies, by inducing tumor cell death and enhancing the immune response.

Chemical Structure

CC-1069
CC-1069
CAS#167887-03-8

Theoretical Analysis

MedKoo Cat#: 145762

Name: CC-1069

CAS#: 167887-03-8

Chemical Formula: C19H18N2O5

Exact Mass: 354.1200

Molecular Weight: 354.36

Elemental Analysis: C, 64.40; H, 5.12; N, 7.91; O, 22.57

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CC-1069; CC-1069; CC 1069;
IUPAC/Chemical Name
3-(3,4-dimethoxyphenyl)-3-(1,3-dioxoisoindolin-2-yl)propanamide
InChi Key
GKPXSGPDRIUIAD-UHFFFAOYSA-N
InChi Code
1S/C19H18N2O5/c1-25-15-8-7-11(9-16(15)26-2)14(10-17(20)22)21-18(23)12-5-3-4-6-13(12)19(21)24/h3-9,14H,10H2,1-2H3,(H2,20,22)
SMILES Code
COC1=C(OC)C=C(C=C1)C(CC(N)=O)N2C(=O)C3=C(C=CC=C3)C2=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 354.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Moreira AL, Friedlander DR, Shif B, Kaplan G, Zagzag D. Thalidomide and a thalidomide analogue inhibit endothelial cell proliferation in vitro. J Neurooncol. 1999 Jun;43(2):109-14. doi: 10.1023/a:1006202700039. PMID: 10533722.