ZD6021 | CAS#255049-08-2 | NK-1 Receptor Antagonist

MedKoo Cat#: 532995 | Name: ZD6021

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ZD6021 is a neurokinin 1 receptor antagonist.

Chemical Structure

ZD6021

CAS#255049-08-2

Theoretical Analysis

MedKoo Cat#: 532995

Name: ZD6021

CAS#: 255049-08-2

Chemical Formula: C35H35Cl2N3O2S

Exact Mass: 631.1827

Molecular Weight: 632.64

Elemental Analysis: C, 66.45; H, 5.58; Cl, 11.21; N, 6.64; O, 5.06; S, 5.07

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

ZD6021; ZD 6021; ZD-6021.

IUPAC/Chemical Name

3-cyano-N-[(2S)-2-(3,4-dichlorophenyl)-4-[4-[2-[(S)-methylsulfinyl]phenyl]piperidin-1-yl]butyl]-N-methylnaphthalene-1-carboxamide

InChi Key

SJHZTGDJTIZMSK-KPRDSAADSA-N

InChi Code

InChI=1S/C35H35Cl2N3O2S/c1-39(35(41)31-20-24(22-38)19-27-7-3-4-8-29(27)31)23-28(26-11-12-32(36)33(37)21-26)15-18-40-16-13-25(14-17-40)30-9-5-6-10-34(30)43(2)42/h3-12,19-21,25,28H,13-18,23H2,1-2H3/t28-,43+/m1/s1

SMILES Code

O=C(C1=C2C=CC=CC2=CC(C#N)=C1)N(C[C@H](C3=CC=C(Cl)C(Cl)=C3)CCN4CCC(C5=CC=CC=C5[S@](C)=O)CC4)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 632.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Lindström E, von Mentzer B, Påhlman I, Ahlstedt I, Uvebrant A, Kristensson E, Martinsson R, Novén A, de Verdier J, Vauquelin G. Neurokinin 1 receptor antagonists: correlation between in vitro receptor interaction and in vivo efficacy. J Pharmacol Exp Ther. 2007 Sep;322(3):1286-93. Epub 2007 Jun 15. PubMed PMID: 17575073.