MedKoo Cat#: 146217 | Name: Swertinin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Swertinin is a bioactive flavonoid compound found in plants of the Swertia genus, commonly used in traditional Ayurvedic and Chinese medicine. It has demonstrated a range of pharmacological activities, including antidiabetic, antioxidant, and hepatoprotective effects. The mechanism of swertinin is thought to involve the regulation of glucose metabolism, enhancement of insulin secretion, and reduction of oxidative stress by modulating key cellular pathways. Its applications lie mainly in the development of herbal formulations and research into natural treatments for diabetes and liver-related disorders.

Chemical Structure

Swertinin
Swertinin
CAS#25991-81-5

Theoretical Analysis

MedKoo Cat#: 146217

Name: Swertinin

CAS#: 25991-81-5

Chemical Formula: C15H12O6

Exact Mass: 288.0634

Molecular Weight: 288.26

Elemental Analysis: C, 62.50; H, 4.20; O, 33.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Swertinin;
IUPAC/Chemical Name
6,8-dihydroxy-1,2-dimethoxy-9H-xanthen-9-one
InChi Key
BEPQKAFKFDCXTR-UHFFFAOYSA-N
InChi Code
1S/C15H12O6/c1-19-10-4-3-9-13(15(10)20-2)14(18)12-8(17)5-7(16)6-11(12)21-9/h3-6,16-17H,1-2H3
SMILES Code
COC1=C(OC)C2=C(OC3=C(C2=O)C(O)=CC(O)=C3)C=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 288.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Biesdorf C, Cortez DA, Audi EA. Assessment of anxiolytic and panicolytic effects of dichloromethane fraction from stems of Kielmeyera coriacea. Phytomedicine. 2012 Feb 15;19(3-4):374-7. doi: 10.1016/j.phymed.2011.08.067. Epub 2011 Oct 4. PMID: 21975171.