VH-937 | HIV‑1 Maturation Inhibitor

MedKoo Cat#: 128062 | Name: VH-937

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VH-937 is a Potent HIV‑1 Maturation Inhibitor with the Potential for Infrequent Oral Dosing in Humans.

Chemical Structure

VH-937

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128062

Name: VH-937

CAS#: N/A

Chemical Formula: C49H72N4O5S

Exact Mass: 828.5223

Molecular Weight: 829.20

Elemental Analysis: C, 70.98; H, 8.75; N, 6.76; O, 9.65; S, 3.87

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

VH-937; VH 937; VH937; VH-3739937; VH 3739937; VH3739937

IUPAC/Chemical Name

(1S)-1-(((3-cyanopyridin-2-yl)oxy)methyl)-4-((1R,3aS,5aR,5bR,7aS,11aS,11bR,13aR,13bR)-3a-((2-(1,1-dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-yl)cyclohex-3-ene-1-carboxylic acid

InChi Key

AXSTZRZGJHMBPZ-DAIYDDBYSA-N

InChi Code

InChI=1S/C49H72N4O5S/c1-33(2)36-14-21-49(52-25-26-53-27-29-59(56,57)30-28-53)23-22-46(6)38(41(36)49)10-11-40-45(5)17-15-37(44(3,4)39(45)16-18-47(40,46)7)34-12-19-48(20-13-34,43(54)55)32-58-42-35(31-50)9-8-24-51-42/h8-9,12,24,36-41,52H,1,10-11,13-23,25-30,32H2,2-7H3,(H,54,55)/t36-,37?,38+,39-,40+,41+,45-,46+,47+,48?,49-/m0/s1

SMILES Code

CC([C@@](CC[C@]1(C)[C@]2([H])CC[C@@]3([H])[C@@]1(C)CC[C@]4(NCCN5CCS(CC5)(=O)=O)[C@]3([H])[C@H](C(C)=C)CC4)([H])[C@]2(C)CC6)(C)C6C7=CC[C@@](COC8=C(C#N)C=CC=N8)(C(O)=O)CC7

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 829.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

McAuliffe B, Falk P, Chen J, Chen Y, Sit SY, Swidorski J, Hartz RA, Xu L, Venables B, Sin N, Meanwell NA, Regueiro-Ren A, Wensel D, Hanumegowda U, Krystal M. Preclinical Profile of the HIV-1 Maturation Inhibitor VH3739937. Viruses. 2024 Sep 24;16(10):1508. doi: 10.3390/v16101508. PMID: 39459843; PMCID: PMC11512352.