Synonym
Chlorin e4; Chlorin-e4;
IUPAC/Chemical Name
(7S,8S)-7-(2-carboxyethyl)-18-ethyl-2,5,8,12,17-pentamethyl-13-vinyl-7H,8H-porphyrin-3-carboxylic acid
InChi Key
BAYNJLMXYJTMOX-XVHHMFMTSA-N
InChi Code
InChI=1S/C33H36N4O4/c1-8-20-15(3)23-12-25-17(5)22(10-11-29(38)39)31(36-25)19(7)32-30(33(40)41)18(6)26(37-32)14-28-21(9-2)16(4)24(35-28)13-27(20)34-23/h8,12-14,17,22,34,37H,1,9-11H2,2-7H3,(H,38,39)(H,40,41)/b23-12-,24-13-,25-12-,26-14-,27-13-,28-14-,31-19-,32-19-/t17-,22-/m0/s1
SMILES Code
CC1=C(CC)/C2=C/C3=C(C)C(C(O)=O)=C(/C(C)=C4[C@@H](CCC(O)=O)[C@H](C)C(/C=C(N/5)/C(C)=C(C=C)C5=C\C1=N2)=N/4)N3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
552.68
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1.) Wang, Xiao-Feng; Kitao, Osamu, Natural chlorophyll-related porphyrins and chlorins for dye-sensitized solar cells, Molecules (2012), 17, 4484-4497.
2.) Fahey Jed W; Stephenson Katherine K; Dinkova-Kostova Albena T; Egner Patricia A; Kensler Thomas W; Talalay Paul, Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes , Carcinogenesis (2005), 26(7), 1247-55.
3.) Egner, Patricia A.; Stansbury, Kevin H.; Snyder, Edward P.; Rogers, Mark E.; Hintz, Paul A.; Kensler, Thomas W., Identification and Characterization of Chlorin e4 Ethyl Ester in Sera of Individuals Participating in the Chlorophyllin Chemoprevention Trial, Chemical Research in Toxicology (2000), 13(9), 900-906.
4.) Vermathen, Martina; Marzorati, Mattia; Bigler, Peter, Self-Assembling Properties of Porphyrinic Photosensitizers and Their Effect on Membrane Interactions Probed by NMR Spectroscopy, Journal of Physical Chemistry B (2013), 117(23), 6990-7001.
 Protoporphyrin IX chloride2032.jpg "Mn(III) Protoporphyrin IX chloride")
