VZN-80448 is a fluorogenic substrate for leucine aminopeptidase. Upon enzymatic cleavage by leucine aminopeptidase, AMC is released and its fluorescence can be used to quantify leucine aminopeptidase activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming).
MedKoo Cat#: 464835
Name: VZN-80448
CAS#: 62480-44-8
Chemical Formula: C16H21ClN2O3
Exact Mass:
Molecular Weight: 324.81
Elemental Analysis: C, 59.17; H, 6.52; Cl, 10.91; N, 8.62; O, 14.78
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMF | 25.0 | 76.97 | |
| DMSO | 25.0 | 76.97 | |
| DMSO:PBS (pH 7.2) (1:3) | 0.3 | 0.77 |
The following data is based on the product molecular weight 324.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
