SB-583355 | CAS#3040121-49-8 | GPR132 antagonist

MedKoo Cat#: 127307 | Name: SB-583355

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SB-583355 is a Potent and Selective G2A (GPR132) antagonist.

Chemical Structure

SB-583355

CAS#3040121-49-8

Theoretical Analysis

MedKoo Cat#: 127307

Name: SB-583355

CAS#: 3040121-49-8

Chemical Formula: C29H32N2O4

Exact Mass: 472.2362

Molecular Weight: 472.59

Elemental Analysis: C, 73.71; H, 6.83; N, 5.93; O, 13.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

SB-583355; SB 583355; SB583355

IUPAC/Chemical Name

(S)-N-(1-(cyclohexylamino)-1-oxo-3-phenylpropan-2-yl)-6-hydroxy-4'-methoxy-[1,1'-biphenyl]-3-carboxamide

InChi Key

LFKOKWUSIRSBHS-SANMLTNESA-N

InChi Code

InChI=1S/C29H32N2O4/c1-35-24-15-12-21(13-16-24)25-19-22(14-17-27(25)32)28(33)31-26(18-20-8-4-2-5-9-20)29(34)30-23-10-6-3-7-11-23/h2,4-5,8-9,12-17,19,23,26,32H,3,6-7,10-11,18H2,1H3,(H,30,34)(H,31,33)/t26-/m0/s1

SMILES Code

OC(C=CC(C(N[C@@H](CC1=CC=CC=C1)C(NC2CCCCC2)=O)=O)=C3)=C3C4=CC=C(OC)C=C4

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 472.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Foster JR, Ueno S, Chen MX, Harvey J, Dowell SJ, Irving AJ, Brown AJ. N-Palmitoylglycine and other N-acylamides activate the lipid receptor G2A/GPR132. Pharmacol Res Perspect. 2019 Nov 21;7(6):e00542. doi: 10.1002/prp2.542. PMID: 31768260; PMCID: PMC6868653.