Globosuxanthone A is cytotoxic to various human solid tumor cell lines, including MCF-7, PC3, LNCap, and DU145 cells (IC50s = 1.3, 0.65, 1.5, and 1.2 µM, respectively) and induces accumulation of cells in the G2/M and S phases of the cell cycle in NCI-H460 and PC3M cells.
MedKoo Cat#: 112101
Name: Globosuxanthone A
CAS#: 917091-74-8
Chemical Formula: C15H12O7
Exact Mass: 304.0583
Molecular Weight: 304.25
Elemental Analysis: C, 59.22; H, 3.98; O, 36.81
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| Ethanol | 1.0 | 3.29 |
The following data is based on the product molecular weight 304.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
