Pargeverine hydrochloride | antispasmodic | CAS#2765-97-1

MedKoo Cat#: 126427 | Name: Pargeverine hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pargeverine (also known as a propinox) is an antispasmodic drug that was studied for the treatment of disorders of the gastrointestinal tract, the uterus, and the gallbladder.

Chemical Structure

Pargeverine hydrochloride

CAS#2765-97-1 (HCl)

Theoretical Analysis

MedKoo Cat#: 126427

Name: Pargeverine hydrochloride

CAS#: 2765-97-1 (HCl)

Chemical Formula: C21H24ClNO3

Exact Mass: 0.0000

Molecular Weight: 373.88

Elemental Analysis: C, 67.46; H, 6.47; Cl, 9.48; N, 3.75; O, 12.84

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

13479-13-5 (free base) 2765-97-1 (HCl)

Synonym

PARGEVERINE HYDROCHLORIDE; PARGEVERIN HYDROCHLORIDE; PARGEVERINE HCL; Pargeverine hydrochloride; PROPINOX HCL; PROPINOX HYDROCHLORIDE

IUPAC/Chemical Name

2-(dimethylamino)ethyl 2,2-diphenyl-2-(prop-2-yn-1-yloxy)acetate hydrochloride

InChi Key

RSBGQTFIHFGTSY-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H23NO3.ClH/c1-4-16-25-21(18-11-7-5-8-12-18,19-13-9-6-10-14-19)20(23)24-17-15-22(2)3;/h1,5-14H,15-17H2,2-3H3;1H

SMILES Code

Cl.CN(C)CCOC(=O)C(OCC#C)(C1=CC=CC=C1)C2=CC=CC=C2

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 373.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: de los Santos AR, Martí ML, Di Girolamo G, Diego Espinosa J, Morano MA, Tobar JC, Del Prete C. Propinox in biliary colic: a multicenter, randomized, prospective and parallel double-blind study of three doses of propinox versus placebo in acute biliary colic pain. Int J Tissue React. 1999;21(1):13-8. PubMed PMID: 10463136. 2: Di Girolamo G, de los Santos AR, Martí ML, Valdés Quintana E, Godoy MI, Morano MA, Palomino G, Fandiño D, Greggio A. Propinox in intestinal colic: multicenter randomized prospective double-blind study of three doses of propinox vs. placebo in acute intestinal colic pain. Int J Clin Pharmacol Res. 2000;20(1-2):31-40. PubMed PMID: 11146900.