Zuretinol acetate | CAS#29584-22-3 | retinoid

MedKoo Cat#: 125978 | Name: Zuretinol acetate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Zuretinol, is the metabolite of Zuretinol acetate, which is also known as QLT091001 and BBP-551, is an oral retinoid. Zuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis).

Chemical Structure

Zuretinol acetate

CAS#29584-22-3 (acetate)

Theoretical Analysis

MedKoo Cat#: 125978

Name: Zuretinol acetate

CAS#: 29584-22-3 (acetate)

Chemical Formula: C22H32O2

Exact Mass: 328.2402

Molecular Weight: 328.50

Elemental Analysis: C, 80.44; H, 9.82; O, 9.74

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

22737-97-9 (free) 29584-22-3 (acetate)

Synonym

Zuretinol acetate; 29584-22-3; 9-cis-Retinol Acetate; 9-cis-Vitamin A acetate; 9-cis-Vitamin A1 acetate; Zuretinol; QLT091001; QLT-091001; QLT 091001

IUPAC/Chemical Name

(2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl acetate

InChi Key

QGNJRVVDBSJHIZ-AQDFTDIISA-N

InChi Code

InChI=1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9-,18-14+

SMILES Code

CC(=O)OC\C=C(C)\C=C\C=C(C)/C=C/C1=C(C)CCCC1(C)C

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 328.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Hussain RM, Gregori NZ, Ciulla TA, Lam BL. Pharmacotherapy of retinal disease with visual cycle modulators. Expert Opin Pharmacother. 2018 Apr;19(5):471-481. doi: 10.1080/14656566.2018.1448060. Epub 2018 Mar 15. Review. PubMed PMID: 29542350.