MedKoo Cat#: 123081 | Name: WAY-320461
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

WAY-320461 is a small-molecule inhibitor targeting focal adhesion kinase (FAK), a non-receptor tyrosine kinase involved in cellular adhesion, migration, and survival. By inhibiting FAK activity, WAY-320461 disrupts signal transduction pathways that are often upregulated in cancer cells, leading to reduced tumor growth and metastasis.

Chemical Structure

WAY-320461
WAY-320461
CAS#491839-65-7

Theoretical Analysis

MedKoo Cat#: 123081

Name: WAY-320461

CAS#: 491839-65-7

Chemical Formula: C15H10BrN3O2S

Exact Mass: 374.9677

Molecular Weight: 376.23

Elemental Analysis: C, 47.89; H, 2.68; Br, 21.24; N, 11.17; O, 8.50; S, 8.52

Price and Availability

Size Price Availability Quantity
100mg USD 950.00 2 Weeks
200mg USD 1,650.00 2 Weeks
500mg USD 2,950.00 2 Weeks
1g USD 4,950.00 2 Weeks
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Related CAS #
No Data
Synonym
FAK-IN-10; WAY-320461;
IUPAC/Chemical Name
1-(4-bromophenyl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)ethan-1-one
InChi Key
RZRDLDDOZNGXJT-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H10BrN3O2S/c16-12-3-1-10(2-4-12)13(20)9-22-15-19-18-14(21-15)11-5-7-17-8-6-11/h1-8H,9H2
SMILES Code
BrC1=CC=C(C(CSC2=NN=C(C3=CC=NC=C3)O2)=O)C=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 376.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Zhang LR, Liu ZJ, Zhang H, Sun J, Luo Y, Zhao TT, Gong HB, Zhu HL. Synthesis, biological evaluation and molecular docking studies of novel 2-(1,3,4-oxadiazol-2-ylthio)-1-phenylethanone derivatives. Bioorg Med Chem. 2012 Jun 1;20(11):3615-21. doi: 10.1016/j.bmc.2012.03.061. Epub 2012 Apr 11. PMID: 22541051.