MedKoo Cat#: 471048 | Name: YE-120
Featured New

Description:

WARNING: This product is for research use only, not for human or veterinary use.

YE-120 is an agonist of G protein-coupled receptor 35 (GPR35).

Chemical Structure

YE-120
YE-120
CAS#383124-82-1

Theoretical Analysis

MedKoo Cat#: 471048

Name: YE-120

CAS#: 383124-82-1

Chemical Formula: C16H9Cl2N3O

Exact Mass: 329.0123

Molecular Weight: 330.17

Elemental Analysis: C, 58.21; H, 2.75; Cl, 21.47; N, 12.73; O, 4.85

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
1g USD 4,450.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
YE-120; YE120; YE 120
IUPAC/Chemical Name
2-[3-cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]-propanedinitrile
InChi Key
RSWZFAPYKOARNG-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H9Cl2N3O/c1-9-12(8-21)15(10(6-19)7-20)22-16(9,2)11-3-4-13(17)14(18)5-11/h3-5H,1-2H3
SMILES Code
N#C/C(C#N)=C1OC(C)(C2=CC=C(Cl)C(Cl)=C2)C(C)=C\1C#N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 330.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Deng H, Hu H, He M, Hu J, Niu W, Ferrie AM, Fang Y. Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists. J Med Chem. 2011 Oct 27;54(20):7385-96. doi: 10.1021/jm200999f. Epub 2011 Oct 4. PMID: 21950657; PMCID: PMC3198121.