Sonlicromanol, also known as KH-176, is potentially for the treatment of mitochondrial diseases. KH-176 is a potent intracellular redox modulating agent targeting the reactive oxygen species which are important in the pathogenesis of disorders of mitochondrial oxidative phosphorylation. The in vivo metabolite of Sonlicromanol, KH176m, acts both as redox-modulator (via mPGES-1 inhibition) and as antioxidant (via Thioredoxin/Peroxiredoxin system).
MedKoo Cat#: 125536
Name: Sonlicromanol HCl
CAS#: 2162149-24-6 (HCl)
Chemical Formula: C19H29ClN2O3
Exact Mass: 368.1900
Molecular Weight: 368.90
Elemental Analysis: C, 61.86; H, 7.92; Cl, 9.61; N, 7.59; O, 13.01
The following data is based on the product molecular weight 368.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
