Sonlicromanol, also known as KH-176, is potentially for the treatment of mitochondrial diseases. KH-176 is a potent intracellular redox modulating agent targeting the reactive oxygen species which are important in the pathogenesis of disorders of mitochondrial oxidative phosphorylation. The in vivo metabolite of Sonlicromanol, KH176m, acts both as redox-modulator (via mPGES-1 inhibition) and as antioxidant (via Thioredoxin/Peroxiredoxin system).
MedKoo Cat#: 558242
Name: Sonlicromanol
CAS#: 1541170-75-5 (free base)
Chemical Formula: C19H28N2O3
Exact Mass: 332.2100
Molecular Weight: 332.44
Elemental Analysis: C, 68.65; H, 8.49; N, 8.43; O, 14.44
The following data is based on the product molecular weight 332.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
