MedKoo Cat#: 125487 | Name: CYY292
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CYY292 is an inhibitor of PDGFRα, PDGFRβ, FGFR1, -2, and -3.

Chemical Structure

CYY292
CYY292
CAS#2644673-04-9

Theoretical Analysis

MedKoo Cat#: 125487

Name: CYY292

CAS#: 2644673-04-9

Chemical Formula: C24H28N8O

Exact Mass: 444.2400

Molecular Weight: 444.54

Elemental Analysis: C, 64.85; H, 6.35; N, 25.21; O, 3.60

Price and Availability

Size Price Availability Quantity
1mg USD 450.00 2 Weeks
5mg USD 750.00 2 Weeks
10mg USD 1,150.00 2 Weeks
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Related CAS #
No Data
Synonym
CYY292; CYY 292; CYY-292
IUPAC/Chemical Name
N4-(1H-indazol-6-yl)-N2-(3-methoxy-4-(4-methylpiperazin-1-yl)phenyl)-5-methylpyrimidine-2,4-diamine
InChi Key
PCQOIBJOKXSDEB-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H28N8O/c1-16-14-25-24(29-23(16)27-18-5-4-17-15-26-30-20(17)12-18)28-19-6-7-21(22(13-19)33-3)32-10-8-31(2)9-11-32/h4-7,12-15H,8-11H2,1-3H3,(H,26,30)(H2,25,27,28,29)
SMILES Code
CN1CCN(C2=CC=C(NC(N=C3NC4=CC(NN=C5)=C5C=C4)=NC=C3C)C=C2OC)CC1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 444.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Bi Y, Zheng R, Hu J, Shi R, Shi J, Wang Y, Wang P, Jiang W, Kim G, Liu Z, Li X, Lin L. A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis. Genes Dis. 2023 Apr 3;11(1):479-494. doi: 10.1016/j.gendis.2023.02.035. PMID: 37588207; PMCID: PMC10425802.