MedKoo Cat#: 471220 | Name: KU-0058948 hydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

KU-0058948 hydrochloride is a poly (ADP-ribose) polymerase (PARP) inhibitor that induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro.

Chemical Structure

KU-0058948 hydrochloride
KU-0058948 hydrochloride
CAS#2108829-86-1 (HCl)

Theoretical Analysis

MedKoo Cat#: 471220

Name: KU-0058948 hydrochloride

CAS#: 2108829-86-1 (HCl)

Chemical Formula: C21H22ClFN4O2

Exact Mass: 0.0000

Molecular Weight: 416.88

Elemental Analysis: C, 60.50; H, 5.32; Cl, 8.50; F, 4.56; N, 13.44; O, 7.68

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
50mg USD 1,050.00 2 Weeks
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Synonym
KU-0058948 hydrochloride; KU0058948 hydrochloride; KU 0058948 hydrochloride; KU-0058948 HCl
IUPAC/Chemical Name
4-(3-(1,4-diazepane-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one hydrochloride
InChi Key
GXROJFUSWNEBPH-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H21FN4O2.ClH/c22-18-7-6-14(12-17(18)21(28)26-10-3-8-23-9-11-26)13-19-15-4-1-2-5-16(15)20(27)25-24-19;/h1-2,4-7,12,23H,3,8-11,13H2,(H,25,27);1H
SMILES Code
O=C1NN=C(CC2=CC=C(F)C(C(N3CCNCCC3)=O)=C2)C4=C1C=CC=C4.[H]Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 416.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL