YCH1899 | PARP inhibitor

MedKoo Cat#: 125250 | Name: YCH1899

Description:

WARNING: This product is for research use only, not for human or veterinary use.

YCH1899 is a PARP inhibitor.

Chemical Structure

YCH1899

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 125250

Name: YCH1899

CAS#: N/A

Chemical Formula: C25H18BrFN6O3

Exact Mass: 548.0600

Molecular Weight: 549.36

Elemental Analysis: C, 54.66; H, 3.30; Br, 14.54; F, 3.46; N, 15.30; O, 8.74

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

YCH1899; YCH-1899; YCH 1899

IUPAC/Chemical Name

4-(3-(3-(5-bromofuran-2-yl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-7-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one

InChi Key

STSCRAGBCYODMY-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H18BrFN6O3/c26-21-8-7-20(36-21)23-30-29-22-13-32(9-10-33(22)23)25(35)17-11-14(5-6-18(17)27)12-19-15-3-1-2-4-16(15)24(34)31-28-19/h1-8,11H,9-10,12-13H2,(H,31,34)

SMILES Code

O=C1NN=C(CC2=CC(C(N3CCN4C(C3)=NN=C4C5=CC=C(Br)O5)=O)=C(F)C=C2)C6=CC=CC=C61

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 549.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Sun Y, Yang H, Yuan J, Wang L, Song S, Chen R, Bao X, Jia L, Yang T, Zhang X, He Q, Gan Y, Miao Z, He J, Yang C. YCH1899, a Highly Effective Phthalazin-1(2H)-one Derivative That Overcomes Resistance to Prior PARP Inhibitors. J Med Chem. 2023 Sep 14;66(17):12284-12303. doi: 10.1021/acs.jmedchem.3c00821. Epub 2023 Aug 21. PMID: 37605459.