MedKoo Cat#: 128893 | Name: L1Au2
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

L1Au2 is a dual inhibitor of EGFR and thioredoxin reductase (TrxR; IC50 = 0.99 µM).

Chemical Structure

L1Au2
L1Au2
CAS#3038386-42-1

Theoretical Analysis

MedKoo Cat#: 128893

Name: L1Au2

CAS#: 3038386-42-1

Chemical Formula: C24H24AuClFN6O2P

Exact Mass: 710.1036

Molecular Weight: 710.88

Elemental Analysis: C, 40.55; H, 3.40; Au, 27.71; Cl, 4.99; F, 2.67; N, 11.82; O, 4.50; P, 4.36

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 850.00 2 Weeks
10mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
L1Au2; Alkynyl-Au(I) Gefitinib; TrxR/EGFR-IN-1
IUPAC/Chemical Name
[3-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-propyn-1-yl](1,3,5-triaza-7-phosphatricyclo[3.3.1.13,7]decane-κP7)-gold
InChi Key
RTPAYNVMOCGXFK-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H12ClFN3O2.C6H12N3P.Au/c1-3-6-25-17-8-12-15(9-16(17)24-2)21-10-22-18(12)23-11-4-5-14(20)13(19)7-11;1-7-2-9-3-8(1)5-10(4-7)6-9;/h4-5,7-10H,6H2,2H3,(H,21,22,23);1-6H2;
SMILES Code
FC(C=C1)=C(Cl)C=C1NC2=NC=NC3=CC(OC)=C(OCC#C[Au][P]4(C5)CN(C6)CN5CN6C4)C=C32
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 710.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL