Pomalidomide-benzyl-piperazine hydrochloride serves a building block in the synthesis of targeted protein degraders and PROTACs. Pomalidomide-benzyl-piperazine hydrochloride is comprised of a Cereblon (CRBN)-recruiting ligand, a rigid linker, and a pendant amine that reacts with a carboxylic acid on the target ligand.
MedKoo Cat#: 130382
Name: Pomalidomide-benzyl-piperazine hydrochloride
CAS#: N/A
Chemical Formula: C25H26ClN5O5
Exact Mass:
Molecular Weight: 511.96
Elemental Analysis: C, 58.65; H, 5.12; Cl, 6.92; N, 13.68; O, 15.63
The following data is based on the product molecular weight 511.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
